• ERLOSAMIDE chembl:CHEMBL58323 Approved

    Alternate Names:

    ADD-243037
    SPM-927
    VIMPAT
    LACOSAMIDE
    ERLOSAMIDE
    VIMPAT®
    ADD 234037
    HARKEROSIDE
    SPM 927
    HARKOSERIDE
    chemidplus:175481-36-4
    drugbank:06218
    rxcui:623400
    pubchem.compound:219078
    chembl:CHEMBL58323

    Drug Info:

    FDA Approval approved
    Drug Class Small molecule
    Drug Indications anticonvulsant,analgesic,neuropathic pain
    (3 More Sources)
  • Interaction Score: 10.63

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Lacosamide
    Novel drug target Established target

    PMIDs:
    None found


  • Interaction Score: 0.18

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    10592235


  • Interaction Score: 0.18

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.16

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

    PMIDs:
    None found


  • Interaction Score: 0.14

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    10592235


  • Interaction Score: 0.1

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.06

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Sodium channel alpha subunit blocker

    PMIDs:
    None found


  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications anticonvulsant,analgesic,neuropathic pain
    Drug Class Small molecule
    FDA Approval approved

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    D05OFX TTD Drug ID

    Drug Info:

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    LACOSAMIDE GuideToPharmacology Ligand Name

    Drug Info:

    Publications:

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications: