NSC-141540 |
VP-16-213 |
TOPOSAR |
VEPESID |
ETOPOSIDE |
TRANS-ETOPOSIDE |
ETOPOSIDO |
VP-16 |
VEPESID® |
ETOPOSIDUM |
9-((4,6-O-ETHYLIDINE-BETA-D-GLUCOPYRANOSYL)OXY)-5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,4-DIMETHYLOXYPHENYL)FURO(3',4'':6,7)NAPTHO-(2,3-D)-1,3-DIOXOL-6(5AH)-ONE |
ETOPOPHOS® |
VP 16-213 |
4'-DEMETHYLEPIPODOPHYLLOTOXIN 9-(4,6-O-(R)-ETHYLIDENE-BETA-D-GLUCOPYRANOSIDE) |
(−)-ETOPOSIDE |
TOPOSAR® |
4-DEMETHYLEPIPODOPHYLLOTOXIN Β-D-ETHYLIDENEGLUCOSIDE |
4-DEMETHYLEPIPODOPHYLLOTOXIN BETA-D-ETHYLIDENEGLUCOSIDE |
(-)-ETOPOSIDE |
pubchem.compound:36462 |
drugbank:00773 |
chembl:CHEMBL44657 |
chemidplus:33419-42-0 |
rxcui:4179 |
FDA Approval | 1983 |
Drug Class | small molecule |
Drug Indications | Antineoplastic Agents |
Drug Categories | podophyllotoxin derivatives |
Drug Categories | podophyllotoxin |
Drug Categories | lignans |
Drug Categories | glucosides |
Year of Approval | 1983 |
Drug Class | antineoplastic agents |
Drug Categories | cardiotoxic antineoplastic agents |
Drug Categories | cytochrome p-450 cyp1a2 substrates with a narrow therapeutic index |
Drug Categories | cytochrome p-450 cyp2e1 substrates with a narrow therapeutic index |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a4 inducers |
Drug Categories | cytochrome p-450 cyp3a4 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a4 substrates with a narrow therapeutic index |
Drug Categories | cytochrome p-450 cyp3a5 substrates |
Drug Categories | cytochrome p-450 cyp3a5 substrates with a narrow therapeutic index |
Drug Categories | cytochrome p-450 enzyme inducers |
Drug Categories | cytochrome p-450 enzyme inhibitors |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | p-glycoprotein inhibitors |
Drug Categories | p-glycoprotein substrates |
Drug Categories | p-glycoprotein substrates with narrow therapeutic index |
Drug Categories | ugt1a1 substrates |
Drug Categories | ugt1a1 substrates with narrow therapeutic index |
inhibitor (inhibitory) |
Direct Interaction? | True |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
n/a |
ETOPOSIDE | DrugBank Drug Name |
33419-42-0 | CAS Number |
Dom-etoposide | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | antineoplastic agents |
ETOPOSIDE | Primary Drug Name |
Drug Class | antineoplastic agents |
Year of Approval | 1983 |
Drug Indications | Antineoplastic Agents |
Drug Class | small molecule |
FDA Approval | 1983 |
C491 | NCI drug code |
CHEMBL44657 | ChEMBL Drug ID |
D0B7EB | TTD Drug ID |
ETOPOSIDE | GuideToPharmacology Ligand Name |