• Interaction Score: 1.82

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name felodipine ,Plendil
    Novel drug target Established target
    Trial Name enalapril + felodipine,Lexxel

  • Interaction Score: 1.27

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name enalapril + felodipine,Lexxel
    Novel drug target Established target
    Trial Name felodipine ,Plendil

  • Interaction Score: 0.83

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2833901


    Sources:
    NCI

  • Interaction Score: 0.67

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name enalapril + felodipine,Lexxel
    Novel drug target Established target
    Trial Name felodipine ,Plendil

  • Interaction Score: 0.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16097363


    Sources:
    NCI

  • Interaction Score: 0.53

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name enalapril + felodipine,Lexxel
    Novel drug target Established target
    Trial Name felodipine ,Plendil

  • Interaction Score: 0.43

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes
    Trial Name felodipine ,Plendil

  • Interaction Score: 0.4

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Mineralocorticoid receptor antagonist
    Direct Interaction yes

    PMIDs:
    18250364


  • Interaction Score: 0.2

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Specific Action of the Ligand Potentiation
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.19

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9187528


    Sources:
    PharmGKB

  • Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC