DGIdb - FESOTERODINE Drug Record

FESOTERODINE chembl:CHEMBL1201764 Approved

Alternate Names:

FESOTERODINE
SPM-8272
TOVIAZ®
SPM-907
chembl:CHEMBL1201764
rxcui:797195
chemidplus:286930-02-7
pubchem.compound:6918558
drugbank:06702

Drug Info:

Drug Class	antispasmodics, urinary
Year of Approval	2008
FDA Approval	approved
Drug Class	Small molecule
Drug Indications	for treatment of overactive bladder syndrome

(1 More Sources)

Publications:

Nilvebrant, 2002, Tolterodine and its active 5-hydroxymethyl metabolite: pure muscarinic receptor antagonists., Pharmacol. Toxicol.
Mansfield et al., 2009, Comparison of receptor binding characteristics of commonly used muscarinic antagonists in human bladder detrusor and mucosa., J. Pharmacol. Exp. Ther.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

FESOTERODINE CHRM3

Interaction Score: 0.71

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name fesoterodine fumarate, SPM 907,Toviaz

Novel drug target Established target

PMIDs:
12076307 11752352

Sources:
TdgClinicalTrial TEND
FESOTERODINE CHRM2

Interaction Score: 0.48

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

PMIDs:
19029429

Sources:
TEND
FESOTERODINE CHRM1

Interaction Score: 0.29

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

PMIDs:
12076307

Sources:
TEND
FESOTERODINE CYP2D6

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB FDA
FESOTERODINE CYP3A4

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB

TEND: FESOTERODINE
- Version: 01-August-2011
Alternate Names:

FESOTERODINE Primary Drug Name

Drug Info:

Year of Approval 2008

Drug Class antispasmodics, urinary

Publications:
TdgClinicalTrial: FESOTERODINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications for treatment of overactive bladder syndrome

Drug Class Small molecule

FDA Approval approved

Publications:
ChemblDrugs: chembl:CHEMBL1201764
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
FDA: Fesoterodine
- Version: 04-September-2020
Alternate Names:

Drug Info:

Publications:
PharmGKB: fesoterodine
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Trial Name	fesoterodine fumarate, SPM 907,Toviaz
Novel drug target	Established target

FESOTERODINE Drug Record

FESOTERODINE chembl:CHEMBL1201764 Approved

Alternate Names:

Drug Info:

Publications:

FESOTERODINE CHRM3

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name fesoterodine fumarate, SPM 907,Toviaz Novel drug target Established target

PMIDs: 12076307 11752352

Sources: TdgClinicalTrial TEND

FESOTERODINE CHRM2

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info:

PMIDs: 19029429

Sources: TEND

FESOTERODINE CHRM1

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info:

PMIDs: 12076307

Sources: TEND

FESOTERODINE CYP2D6

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB FDA

FESOTERODINE CYP3A4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

TEND: FESOTERODINE

Alternate Names: FESOTERODINE Primary Drug Name

Drug Info: Year of Approval 2008 Drug Class antispasmodics, urinary

Publications:

TdgClinicalTrial: FESOTERODINE

Alternate Names:

Drug Info: Drug Indications for treatment of overactive bladder syndrome Drug Class Small molecule FDA Approval approved

Publications:

ChemblDrugs: chembl:CHEMBL1201764

Alternate Names:

Drug Info:

Publications:

FDA: Fesoterodine

Alternate Names:

Drug Info:

Publications:

PharmGKB: fesoterodine

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name fesoterodine fumarate, SPM 907,Toviaz

Novel drug target Established target

PMIDs:
12076307 11752352

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

antagonist (inhibitory)

PMIDs:
19029429

Sources:
TEND

Interaction Types & Directionality:

antagonist (inhibitory)

PMIDs:
12076307

Sources:
TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB FDA

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Alternate Names:

FESOTERODINE Primary Drug Name

Drug Info:

Year of Approval 2008

Drug Class antispasmodics, urinary

Drug Info:

Drug Indications for treatment of overactive bladder syndrome

Drug Class Small molecule

FDA Approval approved