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FLUCONAZOLE Drug Record

  • Summary
  • Interactions
  • Claims
  • FLUCONAZOLE chembl:CHEMBL106 Approved

    Alternate Names:

    CANESTEN ORAL
    DIFLUCAN
    UK-49858
    DIFLUCAN ONE
    DIFLUCAN IN SODIUM CHLORIDE
    FLUCONAZOLE IN SODIUM CHLORIDE
    TRIFLUCAN
    FLUCONAZOLE
    FLUCONAZOLUM
    2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL
    ELAZOR
    BIOZOLE
    FLUCONAZOL
    2,4-DIFLUORO-ALPHA,ALPHA-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL
    chemidplus:86386-73-4
    pubchem.compound:3365
    rxcui:4450
    drugbank:00196
    chembl:CHEMBL106

    Drug Info:

    (1 More Sources)

    Publications:

    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Niwa T et al., 2016, The Effect of Genetic Polymorphism on the Inhibition of Azole Antifungal Agents Against CYP2C9-Mediated Metabolism., J Pharm Sci
    Kelley et al., 2002, Abnormal sterol metabolism in a patient with Antley-Bixler syndrome and ambiguous genitalia., Am. J. Med. Genet.
    Zhang SL et al., 2014, Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP., Bioorg Med Chem Lett
  • FLUCONAZOLE   CYP51A1

    Interaction Score: 13.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12116245


    Sources:
    NCI

  • FLUCONAZOLE   ALB

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25301772


    Sources:
    DTC

  • FLUCONAZOLE   CYP2C9

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26886310 22931300


    Sources:
    DTC PharmGKB

  • FLUCONAZOLE   TARDBP

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FLUCONAZOLE   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FLUCONAZOLE   CYP2C19

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • FLUCONAZOLE   CYP1A2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • FLUCONAZOLE   CYP2D6

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • FLUCONAZOLE   CYP3A4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • NCI: FLUCONAZOLE

    • Version: 14-September-2017

    Alternate Names:
    C500 NCI drug code

    Drug Info:

    Publications:
    Kelley et al., 2002, Abnormal sterol metabolism in a patient with Antley-Bixler syndrome and ambiguous genitalia., Am. J. Med. Genet.

  • DTC: FLUCONAZOLE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL106 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Zhang SL et al., 2014, Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP., Bioorg Med Chem Lett

  • PharmGKB: fluconazole

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Niwa T et al., 2016, The Effect of Genetic Polymorphism on the Inhibition of Azole Antifungal Agents Against CYP2C9-Mediated Metabolism., J Pharm Sci

  • TTD: Fluconazole

    • Version: 2020.06.01

    Alternate Names:
    D09LNI TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL106

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21