• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

FLURAZEPAM Drug Record

  • Summary
  • Interactions
  • Claims
  • FLURAZEPAM chembl:CHEMBL968 Approved

    Alternate Names:

    DALMANE
    FLURAZEPAM
    RO-56901
    RO-5-6901
    FLURAZEPAMUM
    FLURAZÉPAM
    INSUMIN
    DALMADORN
    chembl:CHEMBL968
    drugbank:00690
    rxcui:4501
    pubchem.compound:3393
    chemidplus:17617-23-1

    Drug Info:

    FDA Approval 1970
    Drug Class small molecule
    Drug Indications Hypnotics and Sedatives
    Drug Class hypnotics and sedatives
    Year of Approval 1970
    (1 More Sources)

    Publications:

    Möhler et al., 2002, A new benzodiazepine pharmacology., J. Pharmacol. Exp. Ther.
    Riss et al., 2008, Benzodiazepines in epilepsy: pharmacology and pharmacokinetics., Acta Neurol. Scand.
    Zhu S et al., 2018, Structure of a human synaptic GABA<sub>A</sub> receptor., Nature
    Sigel E et al., 2012, Structure, function, and modulation of GABA(A) receptors., J Biol Chem
    Ambrosi et al., 1986, Effects of acute benzodiazepine administration on growth hormone, prolactin and cortisol release after moderate insulin-induced hypoglycemia in normal women., Psychopharmacology (Berl.)
  • FLURAZEPAM   GABRR3

    Interaction Score: 0.47

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRR2

    Interaction Score: 0.47

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRR1

    Interaction Score: 0.44

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRQ

    Interaction Score: 0.21

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRP

    Interaction Score: 0.2

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRE

    Interaction Score: 0.2

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRA1

    Interaction Score: 0.19

    Interaction Types & Directionality:
    ligand
    positive modulator (activating)
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456 29950725 23038269


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRD

    Interaction Score: 0.19

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRB3

    Interaction Score: 0.19

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRG1

    Interaction Score: 0.19

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRB1

    Interaction Score: 0.19

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   PRL

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3081931


    Sources:
    NCI

  • FLURAZEPAM   GABRA4

    Interaction Score: 0.18

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRA6

    Interaction Score: 0.18

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRB2

    Interaction Score: 0.17

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Novel drug target Established target
    Trial Name -

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRG3

    Interaction Score: 0.16

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Novel drug target Established target
    Trial Name -

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRA5

    Interaction Score: 0.16

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRA3

    Interaction Score: 0.15

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRA2

    Interaction Score: 0.15

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752090 18384456


    Sources:
    TdgClinicalTrial TEND

  • FLURAZEPAM   GABRG2

    Interaction Score: 0.13

    Interaction Types & Directionality:
    potentiator

    Interaction Info:

    PMIDs:
    11752090 18384456


    Sources:
    TEND

  • FLURAZEPAM   TSPO

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • TEND: FLURAZEPAM

    • Version: 01-August-2011

    Alternate Names:
    FLURAZEPAM Primary Drug Name

    Drug Info:
    Year of Approval 1970
    Drug Class hypnotics and sedatives

    Publications:

  • TdgClinicalTrial: FLURAZEPAM

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Hypnotics and Sedatives
    Drug Class small molecule
    FDA Approval 1970

    Publications:

  • NCI: FLURAZEPAM

    • Version: 14-September-2017

    Alternate Names:
    C29060 NCI drug code

    Drug Info:

    Publications:
    Ambrosi et al., 1986, Effects of acute benzodiazepine administration on growth hormone, prolactin and cortisol release after moderate insulin-induced hypoglycemia in normal women., Psychopharmacology (Berl.)

  • TTD: Flurazepam

    • Version: 2020.06.01

    Alternate Names:
    D08XFV TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL968

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21