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GARLIC Drug Record

  • Summary
  • Interactions
  • Claims
  • GARLIC chembl:CHEMBL2108463

    Alternate Names:

    GARLIC
    ALLIUM SATIVUM
    ALLIUM SATIVUM BULB EXTRACT
    B1233
    ALLIUM SATIVUM POWDER
    ALLIUM SATIVUM BULB POWDER
    ALLIUM SATIVUM BULB

    Drug Info:

    (0 More Sources)

    Publications:

    Gurley et al., 2005, Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba., Drugs Aging
    Balasenthil et al., 2002, Apoptosis induction by S-allylcysteine, a garlic constituent, during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis., Cell Biochem. Funct.
    Chung et al., 1998, Effects of garlic compounds diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in strains of Helicobacter pylori from peptic ulcer patients., Am. J. Chin. Med.
    Chung, 1999, Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in human bladder tumor cells., Drug Chem Toxicol
    Mousa et al., 2005, Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53., Nutr Cancer
    Melzig et al., 1995, Inhibition of adenosine deaminase activity of aortic endothelial cells by extracts of garlic (Allium sativum L.)., Pharmazie
    Fukao et al., 2007, Antithrombotic effects of odorless garlic powder both in vitro and in vivo., Biosci. Biotechnol. Biochem.
    Colić et al., 2000, Garlic extracts stimulate proliferation of rat lymphocytes in vitro by increasing IL-2 and IL-4 production., Immunopharmacol Immunotoxicol
    Munday et al., 2001, Relative activities of organosulfur compounds derived from onions and garlic in increasing tissue activities of quinone reductase and glutathione transferase in rat tissues., Nutr Cancer
    Foster et al., An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic., J Pharm Pharm Sci
  • GARLIC   ADA

    Interaction Score: 1.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7604070


    Sources:
    NCI

  • GARLIC   NAT2

    Interaction Score: 1.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9862023 10234471


    Sources:
    NCI

  • GARLIC   TGM2

    Interaction Score: 0.59

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12125104


    Sources:
    NCI

  • GARLIC   IL2RA

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10737264


    Sources:
    NCI

  • GARLIC   PLG

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17213677


    Sources:
    NCI

  • GARLIC   IL2

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10737264


    Sources:
    NCI

  • GARLIC   GSTP1

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11962257


    Sources:
    NCI

  • GARLIC   ABCB1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11466175


    Sources:
    NCI

  • GARLIC   TP53

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16351512


    Sources:
    NCI

  • GARLIC   CYP2D6

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15974642


    Sources:
    NCI

  • NCI: GARLIC

    • Version: 14-September-2017

    Alternate Names:
    C38706 NCI drug code

    Drug Info:

    Publications:
    Fukao et al., 2007, Antithrombotic effects of odorless garlic powder both in vitro and in vivo., Biosci. Biotechnol. Biochem.
    Colić et al., 2000, Garlic extracts stimulate proliferation of rat lymphocytes in vitro by increasing IL-2 and IL-4 production., Immunopharmacol Immunotoxicol
    Melzig et al., 1995, Inhibition of adenosine deaminase activity of aortic endothelial cells by extracts of garlic (Allium sativum L.)., Pharmazie

  • ChemblDrugs: chembl:CHEMBL2108463

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21