• Interaction Score: 0.97

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Hepatocyte growth factor receptor inhibitor
    Direct Interaction yes
    Details of the Assay for Interaction Measured as inhibition of c-MET phosphorylation in MKN45 cells

  • Interaction Score: 0.47

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Measured as inhibition of VEGFR-2 autophosphorylation in HUVEC cells.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Gefitinib + Golvatinib
    Indication/Tumor Type lung adenocarcinoma
    Response Type sensitive

    PMIDs:
    22789825


    Sources:
    JAX-CKB