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HEPTABARBITAL Drug Record

  • Summary
  • Interactions
  • Claims
  • HEPTABARBITAL chembl:CHEMBL468837

    Alternate Names:

    HEPTABARBITAL
    HEPTABARB
    MEDOMINE
    HEPTABARBITONE
    5-CYCLOHEPT-1-EN-1-YL-5-ETHYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE
    HEPTAMALUM
    NOCTYN
    HEPTBARBITAL
    EUDAN
    MEDOMIN
    HEPTAMAL
    HEPTADORM
    MEDAPAN
    HEPTABARBUM
    pubchem.compound:10518
    chemidplus:509-86-4
    chembl:CHEMBL468837
    drugbank:01354

    Drug Info:

    Drug Groups experimental
    Drug Categories anticholinergic agents
    Drug Categories central nervous system depressants
    Drug Categories nicotinic antagonists
    (0 More Sources)

    Publications:

    Yamakura et al., 2001, Anesthetics and ion channels: molecular models and sites of action., Annu. Rev. Pharmacol. Toxicol.
    Krasowski et al., 1999, General anaesthetic actions on ligand-gated ion channels., Cell. Mol. Life Sci.
    Mehta et al., 1999, An update on GABAA receptors., Brain Res. Brain Res. Rev.
    Whiting, 2003, The GABAA receptor gene family: new opportunities for drug development., Curr Opin Drug Discov Devel
    Arias et al., 2005, Anesthetics as chemical tools to study the structure and function of nicotinic acetylcholine receptors., Curr. Protein Pept. Sci.
  • HEPTABARBITAL   GRIK2

    Interaction Score: 0.77

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    11264449 10487207


    Sources:
    DrugBank

  • HEPTABARBITAL   CHRNA4

    Interaction Score: 0.4

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    11264449 16248797 10487207


    Sources:
    DrugBank

  • HEPTABARBITAL   CHRNA7

    Interaction Score: 0.35

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    11264449 16248797 10487207


    Sources:
    DrugBank

  • HEPTABARBITAL   GRIA2

    Interaction Score: 0.35

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    11264449 10487207


    Sources:
    DrugBank

  • HEPTABARBITAL   GABRA1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    potentiator

    Interaction Info:

    PMIDs:
    14579514 11264449 10209232 10487207


    Sources:
    DrugBank

  • HEPTABARBITAL   GABRA6

    Interaction Score: 0.22

    Interaction Types & Directionality:
    potentiator

    Interaction Info:

    PMIDs:
    11264449 10209232


    Sources:
    DrugBank

  • HEPTABARBITAL   GABRA5

    Interaction Score: 0.2

    Interaction Types & Directionality:
    potentiator

    Interaction Info:

    PMIDs:
    11264449 10209232


    Sources:
    DrugBank

  • HEPTABARBITAL   GABRA2

    Interaction Score: 0.19

    Interaction Types & Directionality:
    potentiator

    Interaction Info:

    PMIDs:
    11264449 10209232


    Sources:
    DrugBank

  • HEPTABARBITAL   GABRA3

    Interaction Score: 0.19

    Interaction Types & Directionality:
    potentiator

    Interaction Info:

    PMIDs:
    11264449 10209232


    Sources:
    DrugBank

  • HEPTABARBITAL   GABRA4

    Interaction Score: 0.15

    Interaction Types & Directionality:
    potentiator

    Interaction Info:

    PMIDs:
    10209232


    Sources:
    DrugBank

  • DrugBank: DB01354

    • Version: 5.1.7

    Alternate Names:
    HEPTABARBITAL DrugBank Drug Name
    509-86-4 CAS Number
    Medomin Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups experimental
    Drug Categories anticholinergic agents

    Publications:
    Yamakura et al., 2001, Anesthetics and ion channels: molecular models and sites of action., Annu. Rev. Pharmacol. Toxicol.
    Krasowski et al., 1999, General anaesthetic actions on ligand-gated ion channels., Cell. Mol. Life Sci.
    Whiting, 2003, The GABAA receptor gene family: new opportunities for drug development., Curr Opin Drug Discov Devel

  • TTD: Heptabarbital

    • Version: 2020.06.01

    Alternate Names:
    D03WAJ TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL468837

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21