DGIdb - HYDROCORTISONE Drug Record

HYDROCORTISONE chembl:CHEMBL389621 ApprovedImmunotherapy

Alternate Names:

H-CORT
NYBADEX
PROCTOCREAM HC
SENTIAL HC
DOME-CORT
NUTRACORT
ELDECORT
BETA-HC
PROCTOCORT
EFCORTELAN P
TERRA-CORTRIL NYSTATIN
BALNEOL-HC
PERINAL
CORLAN
ECONACORT
HC (HYDROCORTISONE)
HC #1
HYDRODERM
ALPHADERM
HYDROCORTISONE IN ABSORBASE
ANUCORT-HC
LOCOID
MEDICORT
COLOCORT
U-CORT
HYDRO-RX
CORT-DOME
CORTISOL
PROCTOFOAM HC
ZENOXONE
CORTENEM
HYTONE
XYLOPROCT
NEO-CORTEF
MILDISON LIPOCREAM
ANFLAM
ALA-SCALP
GREGODERM
OTOSEPTIL
FLEXICORT
COBADEX
PLENADREN
DIODERM
EXE-CORT
PROCTOSEDYL
CORTEF
CORTENEMA
TOPISONE
STIE-CORT
ANUSOL-HC
DERMASPRAY DEMANG
AEROSEB-HC
QUINOCORT
PENECORT
UNIROID
CORTIFOAM
ACTICORT
DERMA CARE HYDROCORT
OTOSPORIN
HYDROCORT IN CALAMINE OILY
HYDROCORTONE
GERMOLOIDS HC
CALMURID HC
CIPRO HC
EPICORT
JUNGLE FOR
TERRA-CORTRIL
TIMODINE
HC45
UNIROID HC
TRI-CICATRIN
CETACORT
COR-OTICIN
EURAX-HYDROCORT
HYDROCORT IN WTE SOFT PARAF
GLYCORT
DAKTACORT HYDROCORT
CORTRIL
ACETASOL HC
ANUGESIC HC
HYDROCORTISONE
CANESTEN HC
DAKTACORT
NYSTAFORM-HC
HYDRODERM HC
HI-COR
NOGENIC HC
SYNACORT
EURAX-HC
TEXACORT
ANUSOL PLUS HC
ALA-CORT
TIMOCORT
ANUSOL HC
HYDROCORT IN CETOMACROGOL FOR A
NSC-10483
OPHTHOCORT
ANUSOL SOOTHING RELIEF
EVACORT
HC #4
DERMACORT
MICORT-HC
drugbank:DB00741
chemidplus:50-23-7
chembl:CHEMBL389621
pubchem.compound:5754
HYDRO-COLISONA
CORTISPRAY
CORTIMENT
AEROSEB HC
FICORTRIL
INCORTIN-HYDROGEN
HYDRO-ADRESON
TOPICORT
SYSTRAL HYDROCORT
CREMICORT-H
ALACORT
AQUACORT
IDROCORTISONE
DELACORT
SCALPICIN CAPILAR
HEB-CORT
SANATISON
KENDALL'S COMPOUND F
OTOSONE-F
BARSEB HC
HYDROCORTISONE ALCOHOL
CORTISOL ALCOHOL
HYDROCORTISTAB
HYCORT
CORTIZOL
11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE
POLCORT H
ESIDERM H
HIDROCORTISONA
17-HYDROXYCORTICOSTERONE
LACTISONA
CALDECORT SPRAY
4-PREGNENE-11B,17A,21-TRIOL-3,20-DIONE
EFCORTELIN
DROTIC
COMPOUND F
UNIDERM
RECTOID
AMBERIN
4-PREGNEN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE
PERMICORT
TRANSDERMA H
VOSOL HC
11Β-HYDROCORTISONE
VYTONE
CORTOLOTION
CORTESAL
MILDISON
PLENADREN®
CHRONOCORT
HYDRACORT
CORTISOLONUM
HC
HYDROCORTISONUM
HYDROCORT
CORTIFAN
CORTISPORIN
PREPCORT
11B-HYDROCORTISONE
OPTEF
KYYPAKKAUS
11-BETA-HYDROCORTISONE
HYCORTOLE
FIOCORTRIL
HYDROXYCORTISONE
CORTANAL
HIDRO-COLISONA
CORT-QUIN
TRAUMAIDE
HYDROCORTICOSTERONE
HYDROSKIN
OTOBIOTIC
HYSONE
ALGICIRTIS
LACTICARE HC
DERMOLATE
HYTONE LOTION
STIEFCORCIL
ANTI-INFLAMMATORY HORMONE
17ALPHA-HYDROXYCORTICOSTERONE
HYCORTOL
11BETA,17,21-TRIHYDROXYPROGESTERONE
CORTOXIDE
DOMOLENE-HC
DERMIL
AQUANIL HC
MAINTASONE
MEUSICORT
MILLIDERM
GENACORT
RACET
11-HYDROCORTISONE
CLEAR AID
11BETA-HYDROXYCORTISONE
COR-TAR-QUIN
NEOSPORIN-H EAR
ACTICO МИХАИЛRT®
CORTICREME
HYDROCORTISONE BASE
FOILLE INSETTI
HYDROCORTAL
HYDROCORTISYL
INCORTIN-H
CORTONEMA
DERM-AID
SCHERICUR
LUBRICORT
CREMESONE
CUTISOL
(11ALPHA,14BETA)-11,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE
11B-HYDROXYCORTISONE
PREPARATION H HYDROCORTISONE CREAM
EPIDERM H
HYDRASSON
4-PREGNENE-11ALPHA,21-TRIOL 3,20-DIONE
BASAN-CORTI
OTIC-NEO-CORT-DOME
EFCORTELAN
11-BETA-HYDROXYCORTISONE
HYDROCORTISONE FREE ALCOHOL
11BETA-HYDROCORTISONE
OTALGINE
HIDALONE
SIGMACORT
EF CORLIN
DIHYDROCOSTISONE
LACTICARE-HC
CLEITON
PRESTWICK_265
TARCORTIN
HYTISONE
(1S,2R,10S,11S,14S,15S,17S)-14,17-DIHYDROXY-14-(2-HYDROXYACETYL)-2,15-DIMETHYLTETRACYCLO[8.7.0.0^{2,7}.0^{11,15}]HEPTADEC-6-EN-5-ONE
ELDERCORT
SIGNEF
REMEDERM HC
PREVEX HC
SCHEROSON F
HEB CORT
KOMED HC
OTOCORT
(11BETA)-11,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE
EFCORBIN
REICHSTEIN'S SUBSTANCE M
NEO-CORT-DOME
PROCTOFOAM
GYNO-CORTISONE
PROTOCORT
17A-HYDROXYCORTICOSTERONE
CORTISPORIN OTICO
11ALPHA-HYDROXYCORTICOSTERONE
PEDIOTIC SUSPENSION
11B,17,21-TRIHYDROXYPROGESTERONE
VIOFORM-HYDROCORTISONE
11A-HYDROXYCORTICOSTERONE
drugbank:00741
rxcui:5492

Drug Info:

(3 More Sources)

Publications:

Tsukamoto et al., 1989, Effect of glucocorticoid on liver regeneration after partial hepatectomy in the rat., Gut
Stuhlmeier et al., 2004, Glucocorticoids inhibit induced and non-induced mRNA accumulation of genes encoding hyaluronan synthases (HAS): hydrocortisone inhibits HAS1 activation by blocking the p38 mitogen-activated protein kinase signalling pathway., Rheumatology (Oxford)
Kelly et al., 2005, Coregulatory protein-orphan nuclear receptor interactions in the human adrenal cortex., J. Endocrinol.
Grossman et al., 2006, Cognitive effects of intravenous hydrocortisone in subjects with PTSD and healthy control subjects., Ann. N. Y. Acad. Sci.
Rautanen et al., 2006, Associations of body size at birth with late-life cortisol concentrations and glucose tolerance are modified by haplotypes of the glucocorticoid receptor gene., J. Clin. Endocrinol. Metab.
Hammer et al., 2006, Cortisol metabolism in hypertension., Best Pract. Res. Clin. Endocrinol. Metab.
Shaw et al., 2007, Role of glucocorticoid receptor in acclimation of killifish (Fundulus heteroclitus) to seawater and effects of arsenic., Am. J. Physiol. Regul. Integr. Comp. Physiol.
Sher, 2006, Combined dexamethasone suppression-corticotropin-releasing hormone stimulation test in studies of depression, alcoholism, and suicidal behavior., ScientificWorldJournal
Schuster D et al., 2006, The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening., J Med Chem
Czock D et al., 2005, Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids., Clin Pharmacokinet
Karlan et al., 1994, Glucocorticoids stabilize HER-2/neu messenger RNA in human epithelial ovarian carcinoma cells., Gynecol. Oncol.
Freeman et al., 1990, Urokinase- and tissue-type plasminogen activators are suppressed by cortisol in the involuting prostate of castrated rats., Biochem. J.
Charles et al., 1995, Central C-type natriuretic peptide augments the hormone response to hemorrhage in conscious sheep., Peptides
Lumbers et al., 2005, Effects of cortisol on cardiac myocytes and on expression of cardiac genes in fetal sheep., Am. J. Physiol. Regul. Integr. Comp. Physiol.
White et al., 1991, Hydrocortisone inhibits rat basophilic leukemia cell mediator release induced by neutrophil-derived histamine releasing activity as well as by anti-IgE., J. Immunol.
Serres et al., 1994, Expression of annexin I in freshly isolated human epidermal cells and in cultured keratinocytes., Arch. Dermatol. Res.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Sato-Matsumura et al., 2000, Membrane expression of annexin I is enhanced by calcium and TPA in cultured human keratinocytes., Arch. Dermatol. Res.
Kononenko et al., [The effect of hydrocortisone on the activity of 5'-nucleotidase and adenosine deaminase in the hypothalamus and hippocampus of the rat brain]., Probl Endokrinol (Mosk)
Smit et al., 2005, Differential regulation of synthetic glucocorticoids on gene expression levels of glucocorticoid-induced leucine zipper and interleukin-2., J. Clin. Endocrinol. Metab.
Lebrethon et al., 1994, Regulation of corticotropin and steroidogenic enzyme mRNAs in human fetal adrenal cells by corticotropin, angiotensin-II and transforming growth factor beta 1., Mol. Cell. Endocrinol.
Belloni et al., 2007, Galanin stimulates cortisol secretion from human adrenocortical cells through the activation of galanin receptor subtype 1 coupled to the adenylate cyclase-dependent signaling cascade., Int. J. Mol. Med.
Nakane et al., 1990, Effects of IL-1 and cortisol on beta-adrenergic receptors, cell proliferation, and differentiation in cultured human A549 lung tumor cells., J. Immunol.
Abbott et al., 1999, RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone., Toxicol. Sci.
Delany et al., 1995, Cortisol increases interstitial collagenase expression in osteoblasts by post-transcriptional mechanisms., J. Biol. Chem.
Sjöberg et al., 1992, Effects of growth hormone on apolipoprotein-B (apoB) messenger ribonucleic acid editing, and apoB 48 and apoB 100 synthesis and secretion in the rat liver., Endocrinology
Peret et al., 1976, Influence of diet, cortisol and insulin on the activity of pyruvate carboxylase and phosphoenolpyruvate carboxykinase in the rat liver., J. Nutr.
Pereira et al., 2002, Cortisol regulates the expression of Notch in osteoblasts., J. Cell. Biochem.
Mark et al., 2006, P-glycoprotein restricts access of cortisol and dexamethasone to the glucocorticoid receptor in placental BeWo cells., Endocrinology
Sun et al., 2007, Beneficial effects of hydrocortisone in induced acute pancreatitis of rats., Chin. Med. J.
George et al., 1998, Mechanism of all trans-retinoic acid and glucocorticoid regulation of surfactant protein mRNA., Am. J. Physiol.
Toebak et al., 2008, Differential suppression of dendritic cell cytokine production by anti-inflammatory drugs., Br. J. Dermatol.
Lee et al., 1991, Effect of glucocorticoids and 1,25-dihydroxyvitamin D3 on the developmental expression of the rat intestinal vitamin D receptor gene., Endocrinology
Guerrero et al., 2004, Hydrocortisone and deflazacort induce different effects on vitamin D receptor level increase produced by 1,25-dihydroxyvitamin D3 in rat osteoblast-like UMR-106 cells., J. Rheumatol.
Ogias et al., 2006, Corticosteroids induce the differential expression of TGFbeta isoforms, receptors and signaling in the gastric mucosa of suckling rats., Regul. Pept.
Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev
Olson et al., 1991, Negative regulation of angiotensinogen gene expression by glucocorticoids in fetal sheep liver., Pediatr. Res.
Smith et al., 2000, Periovulatory human oocytes, cumulus cells, and ovarian leukocytes express type 1 but not type 2 11beta-hydroxysteroid dehydrogenase RNA., Fertil. Steril.
Quinkler et al., 2004, Molecular basis for the apparent mineralocorticoid excess syndrome in the Oman population., Mol. Cell. Endocrinol.
Quinkler et al., 2003, Hypertension and the cortisol-cortisone shuttle., J. Clin. Endocrinol. Metab.
Masera et al., [The autocrine-paracrine modulation of natural killer activity in man by peptides of the corticostatin-defensin family]., Ann. Ital. Med. Int.

HYDROCORTISONE HSD11B2

Interaction Score: 5.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15134813 12788832

Sources:
NCI
HYDROCORTISONE DEFA1

Interaction Score: 3.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8353023

Sources:
NCI
HYDROCORTISONE JAG1

Interaction Score: 3.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11948681

Sources:
NCI
HYDROCORTISONE PC

Interaction Score: 3.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
942746

Sources:
NCI
HYDROCORTISONE HAS3

Interaction Score: 3.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
13130151

Sources:
NCI
HYDROCORTISONE TSC22D3

Interaction Score: 1.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15728202

Sources:
NCI
HYDROCORTISONE ARNT

Interaction Score: 1.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10048155

Sources:
NCI
HYDROCORTISONE GAL

Interaction Score: 0.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17982695

Sources:
NCI
HYDROCORTISONE ANXA1

Interaction Score: 0.5

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
1712816 8060156 17016423 17139284 11142771

Sources:
NCI
HYDROCORTISONE F9

Interaction Score: 0.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1945565

Sources:
NCI
HYDROCORTISONE CCL17

Interaction Score: 0.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18028503

Sources:
NCI
HYDROCORTISONE SFTPA1

Interaction Score: 0.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9575874

Sources:
NCI
HYDROCORTISONE SMAD2

Interaction Score: 0.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16644034

Sources:
NCI
HYDROCORTISONE NR5A1

Interaction Score: 0.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16002533

Sources:
NCI
HYDROCORTISONE ITGAM

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18028766

Sources:
NCI
HYDROCORTISONE NPPC

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7716064

Sources:
NCI
HYDROCORTISONE ADA

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2395837

Sources:
NCI
HYDROCORTISONE PTPRC

Interaction Score: 0.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10731548

Sources:
NCI
HYDROCORTISONE AGT

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15576665

Sources:
NCI
HYDROCORTISONE NOTCH1

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11948681

Sources:
NCI
HYDROCORTISONE MMP1

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7592884

Sources:
NCI
HYDROCORTISONE APOB

Interaction Score: 0.19

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1597147

Sources:
NCI
HYDROCORTISONE NR3C1

Interaction Score: 0.13

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Glucocorticoid receptor agonist

Direct Interaction yes

PMIDs:
16891588 16895953 16980198 17038445 17086345 16759088 15634032

Sources:
DTC ChemblInteractions TTD
HYDROCORTISONE PLAU

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2115769

Sources:
NCI
HYDROCORTISONE IL1B

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2162889

Sources:
NCI
HYDROCORTISONE TGFB1

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7895901

Sources:
NCI
HYDROCORTISONE TYMS

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2707640

Sources:
NCI
HYDROCORTISONE ERBB2

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7909787

Sources:
NCI
HYDROCORTISONE ABCB1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16873536

Sources:
NCI PharmGKB
HYDROCORTISONE NFKB1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HYDROCORTISONE NR1I2

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
HYDROCORTISONE HIF1A

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HYDROCORTISONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1647304 14705237

Sources:
NCI
HYDROCORTISONE HSD17B10

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HYDROCORTISONE CYP3A4

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9187528

Sources:
PharmGKB
HYDROCORTISONE NFE2L2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HYDROCORTISONE AR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

NCI: CORTISOL

Version: 14-September-2017

Alternate Names:

C555 NCI drug code

Drug Info:

Publications:

Kelly et al., 2005, Coregulatory protein-orphan nuclear receptor interactions in the human adrenal cortex., J. Endocrinol.

Pereira et al., 2002, Cortisol regulates the expression of Notch in osteoblasts., J. Cell. Biochem.

Masera et al., [The autocrine-paracrine modulation of natural killer activity in man by peptides of the corticostatin-defensin family]., Ann. Ital. Med. Int.

NCI: HYDROCORTISONE

Version: 14-September-2017

Alternate Names:

C555 NCI drug code

Drug Info:

Publications:

Tsukamoto et al., 1989, Effect of glucocorticoid on liver regeneration after partial hepatectomy in the rat., Gut

Smit et al., 2005, Differential regulation of synthetic glucocorticoids on gene expression levels of glucocorticoid-induced leucine zipper and interleukin-2., J. Clin. Endocrinol. Metab.

Sun et al., 2007, Beneficial effects of hydrocortisone in induced acute pancreatitis of rats., Chin. Med. J.

DTC: HYDROCORTISONE
- Version: 02-September-2020
Alternate Names:

CHEMBL389621 ChEMBL Drug ID

Drug Info:

Publications:

Schuster D et al., 2006, The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening., J Med Chem
PharmGKB: hydrocortisone
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev
TTD: Hydrocortisone
- Version: 2020.06.01
Alternate Names:

D0KR5B TTD Drug ID

Drug Info:

Publications:
ChemblInteractions: CHEMBL389621
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL389621
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Mechanism of Interaction	Glucocorticoid receptor agonist
Direct Interaction	yes

HYDROCORTISONE Drug Record

HYDROCORTISONE chembl:CHEMBL389621 ApprovedImmunotherapy

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15134813 12788832

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8353023

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11948681

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 942746

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 13130151

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15728202

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10048155

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17982695

Sources: NCI

Interaction Types & Directionality: agonist (activating)

Interaction Info:

PMIDs: 1712816 8060156 17016423 17139284 11142771

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1945565

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18028503

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9575874

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16644034

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16002533

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18028766

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7716064

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2395837

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10731548

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15576665

Interaction Types & Directionality:

n/a

PMIDs:
15134813 12788832

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8353023

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11948681

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
942746

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
13130151

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15728202

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10048155

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
17982695

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

PMIDs:
1712816 8060156 17016423 17139284 11142771

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1945565

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
18028503

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9575874

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16644034

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16002533

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
18028766

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7716064

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2395837

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10731548

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15576665

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11948681

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7592884

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1597147

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Glucocorticoid receptor agonist

Direct Interaction yes

PMIDs:
16891588 16895953 16980198 17038445 17086345 16759088 15634032

Sources:
DTC ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
2115769

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2162889

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7895901

Sources:
NCI

Interaction Types & Directionality:

n/a