ABT-348 |
A-968660.0 |
ABBOTT-968660 |
ILORASERTIB |
ABT-348, A-968660 |
A-968660 |
chembl:CHEMBL1980297 |
chemidplus:1227939-82-3 |
pubchem.compound:46207586 |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase Aurora inhibitor |
Direct Interaction | yes |
Direct Interaction? | False |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Details of the Assay for Interaction | Measuring inhibition of kinase activity in a biochemical assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | SRC inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | SRC inhibitor |
n/a |
Drug family | AURKA-VEGF inhibitor |
Alteration | CDKN2A:. |
Alteration | CDKN2A:del |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Details of the Assay for Interaction | Measuring inhibition of kinase activity in a biochemical assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | SRC inhibitor |
inhibitor (inhibitory) |
Details of the Assay for Interaction | Measuring inhibition of kinase activity in a biochemical assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Details of the Assay for Interaction | Measuring inhibition of kinase activity in a biochemical assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Details of the Assay for Interaction | Measuring inhibition of kinase activity in a biochemical assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Details of the Assay for Interaction | Measuring inhibition of kinase activity in a biochemical assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Details of the Assay for Interaction | Measuring inhibition of kinase activity in a biochemical assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Mechanism of Interaction | Vascular endothelial growth factor receptor inhibitor |
Direct Interaction | yes |
Details of the Assay for Interaction | Measuring inhibition of kinase activity in a biochemical assay. |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
CHEMBL1980297 | ChEMBL Drug ID |
D08HOM | TTD Drug ID |
ILORASERTIB | GuideToPharmacology Ligand Name |