DGIdb - IONOMYCIN Drug Record

IONOMYCIN chembl:CHEMBL501617

Alternate Names:

IONOMYCIN

Drug Info:

(0 More Sources)

Publications:

Ziegler et al., 1990, Ca2+ potentiates cAMP-dependent expression of urokinase-type plasminogen activator gene through a calmodulin- and protein kinase C-independent mechanism., J. Biol. Chem.
Fan et al., 2005, G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II., J. Biol. Chem.
Condon et al., 2002, Calmodulin-dependent kinase I regulates adrenal cell expression of aldosterone synthase., Endocrinology
Ojuka, 2004, Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle., Proc Nutr Soc
Conus et al., 1998, Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k., J. Biol. Chem.
Waldron et al., 1997, Store-operated Ca2+ entry and coupling to Ca2+ pool depletion in thapsigargin-resistant cells., J. Biol. Chem.
Amino et al., 2002, Nerve growth factor enhances neurotransmitter release from PC12 cells by increasing Ca(2+)-responsible secretory vesicles through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase., J. Biochem.
Okamoto et al., 1994, The interleukin-8 AP-1 and kappa B-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization., J. Biol. Chem.
Matuszyk et al., 1998, Thymic lymphomas are resistant to Nur77-mediated apoptosis., Biochem. Biophys. Res. Commun.
Kochel et al., 2005, Nur77 nuclear import and its NBRE-binding activity in thymic lymphoma cells are regulated by different mechanisms sensitive to FK506 or HA1004., Biochem. Biophys. Res. Commun.
Teutsch et al., 1995, Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin., Int. Immunol.

IONOMYCIN CD5

Interaction Score: 3.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7540861

Sources:
NCI
IONOMYCIN NR4A1

Interaction Score: 2.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9705872 16051191

Sources:
NCI
IONOMYCIN CAMK2B

Interaction Score: 1.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15845548 12193581

Sources:
NCI
IONOMYCIN TGM2

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9045668

Sources:
NCI
IONOMYCIN PLAU

Interaction Score: 0.53

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1701176

Sources:
NCI
IONOMYCIN CXCL8

Interaction Score: 0.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7510691

Sources:
NCI
IONOMYCIN BDNF

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12038986

Sources:
NCI
IONOMYCIN PIK3CG

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9468542

Sources:
NCI
IONOMYCIN NFE2L2

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15294043

Sources:
NCI

NCI: IONOMYCIN

Version: 14-September-2017

Alternate Names:

C596 NCI drug code

Drug Info:

Publications:

Teutsch et al., 1995, Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin., Int. Immunol.

Okamoto et al., 1994, The interleukin-8 AP-1 and kappa B-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization., J. Biol. Chem.

Kochel et al., 2005, Nur77 nuclear import and its NBRE-binding activity in thymic lymphoma cells are regulated by different mechanisms sensitive to FK506 or HA1004., Biochem. Biophys. Res. Commun.

ChemblDrugs: chembl:CHEMBL501617
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

IONOMYCIN Drug Record

IONOMYCIN chembl:CHEMBL501617

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7540861

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9705872 16051191

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15845548 12193581

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9045668

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1701176

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7510691

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12038986

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9468542

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15294043

Sources: NCI

NCI: IONOMYCIN

Alternate Names: C596 NCI drug code

Drug Info:

ChemblDrugs: chembl:CHEMBL501617

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
7540861

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9705872 16051191

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15845548 12193581

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9045668

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1701176

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7510691

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12038986

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9468542

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15294043

Sources:
NCI

Alternate Names:

C596 NCI drug code