BMS-247550 |
BMS-247550-01 |
IXEMPRA KIT |
IXEMPRA |
IXABEPILONE |
AZA-EPOTHILONE B |
AZAEPOTHILONE B |
chembl:CHEMBL1201752 |
pubchem.compound:6445540 |
drugbank:04845 |
chemidplus:219989-84-1 |
rxcui:337523 |
FDA Approval | not approved |
Drug Class | Small molecule |
Drug Indications | antineoplastic agent |
Drug Class | antineoplastic agent |
Year of Approval | 2007 |
Drug Categories | anti-bacterial agents |
Drug Categories | cytochrome p-450 cyp3a inhibitors |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a4 substrates with a narrow therapeutic index |
Drug Categories | cytochrome p-450 enzyme inhibitors |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | immunosuppressive agents |
Drug Categories | microtubule inhibition |
Drug Categories | microtubule inhibitors |
Drug Categories | narrow therapeutic index drugs |
Drug Categories | p-glycoprotein inhibitors |
Drug Categories | p-glycoprotein substrates |
Drug Categories | p-glycoprotein substrates with narrow therapeutic index |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | ixabepilone, BMS-247550,Ixempra |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Direct Interaction? | True |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
IXABEPILONE | DrugBank Drug Name |
219989-84-1 | CAS Number |
Ixempra | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Groups | investigational |
IXABEPILONE | Primary Drug Name |
Year of Approval | 2007 |
Drug Class | antineoplastic agent |
Drug Indications | antineoplastic agent |
Drug Class | Small molecule |
FDA Approval | not approved |
C37452 | NCI drug code |
D0W2EK | TTD Drug ID |
IXABEPILONE | GuideToPharmacology Ligand Name |