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LABRADIMIL Drug Record

  • Summary
  • Interactions
  • Claims
  • LABRADIMIL chembl:CHEMBL2105864

    Alternate Names:

    RMP-7
    LOBRADIMIL
    LABRADIMIL

    Drug Info:

    (0 More Sources)

    Publications:

    Emerich DF et al., 2001, Bradykinin modulation of tumor vasculature: I. Activation of B2 receptors increases delivery of chemotherapeutic agents into solid peripheral tumors, enhancing their efficacy., J Pharmacol Exp Ther
    Emerich DF et al., 2001, The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier: from concept to clinical evaluation., Clin Pharmacokinet
    Emerich DF et al., 2001, Bradykinin modulation of tumor vasculature: II. activation of nitric oxide and phospholipase A2/prostaglandin signaling pathways synergistically modifies vascular physiology and morphology to enhance delivery of chemotherapeutic agents to tumors., J Pharmacol Exp Ther
  • LABRADIMIL   BDKRB2

    Interaction Score: 20.61

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Bradykinin B2 receptor agonist
    Direct Interaction yes

    PMIDs:
    11160651 11286321 11160652


    Sources:
    ChemblInteractions

  • ChemblDrugs: chembl:CHEMBL2105864

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL2105864

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21