• LIFITEGRAST chembl:CHEMBL2048028 Approved

    Alternate Names:

    SHP606
    XIIDRA
    SAR-1118
    LIFITEGRAST
    SHP-606
    SAR 1118
    SAR-1118-023
    COMPOUND 1G [PMID: 24900456]
    XIIDRA®
    SAR1118
    chemidplus:1025967-78-5
    drugbank:11611
    pubchem.compound:11965427
    rxcui:1801820
    chembl:CHEMBL2048028
  • Interaction Score: 8.51

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC TTD

  • Interaction Score: 5.0

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

  • Interaction Score: 1.12

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Integrin alpha-L/beta-2 (LFA-1) antagonist
    Direct Interaction yes

    PMIDs:
    None found