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LOBELINE Drug Record

  • Summary
  • Interactions
  • Claims
  • LOBELINE chembl:CHEMBL122270

    Alternate Names:

    ALPHA-LOBELINE HCL
    LOBELINE
    ALPHA-LOBELINE
    LOBELINE HCL
    (-)-LOBELINE

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications for treatment of metamphetamine addicton
    (0 More Sources)

    Publications:

    Briggs CA et al., 1998, Activation and inhibition of the human alpha7 nicotinic acetylcholine receptor by agonists., Neuropharmacology
  • LOBELINE   CHRNA9

    Interaction Score: 2.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DrugBank

  • LOBELINE   CHRNA10

    Interaction Score: 1.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DrugBank

  • LOBELINE   SLC18A2

    Interaction Score: 0.84

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Established target
    Trial Name Lobeline

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial TTD

  • LOBELINE   CHRNA7

    Interaction Score: 0.44

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9833639


    Sources:
    DrugBank

  • DrugBank: DB05137

    • Version: 5.1.7

    Alternate Names:
    90-69-7 CAS Number
    CHEMBL122270 ChEMBL ID

    Drug Info:
    Drug Type small molecule
    Drug Groups investigational
    Drug Categories alkaloids

    Publications:
    Briggs CA et al., 1998, Activation and inhibition of the human alpha7 nicotinic acetylcholine receptor by agonists., Neuropharmacology

  • TdgClinicalTrial: LOBELINE

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications for treatment of metamphetamine addicton
    Drug Class Small molecule
    FDA Approval not approved

    Publications:

  • TTD: Lobeline

    • Version: 2020.06.01

    Alternate Names:
    D01IVE TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL122270

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2021-04-13