DGIdb - LUMINESPIB Drug Record

LUMINESPIB chembl:CHEMBL252164

Alternate Names:

NVP-AUY922
NVP-AUY-922
LUMINESPIB
NVP-AUY922-NX
VER-52296

Drug Info:

(1 More Sources)

Publications:

Shaw et al., 2016, Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F., N. Engl. J. Med.
Chen D et al., 2014, Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors., Eur J Med Chem

LUMINESPIB TRAP1

Interaction Score: 15.95

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Inhibition

PMIDs:
None found

Sources:
GuideToPharmacology
LUMINESPIB ALK

Interaction Score: 0.56

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26698910

Sources:
CIViC
LUMINESPIB HSP90AB1

Interaction Score: 0.42

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
LUMINESPIB HSP90AA1

Interaction Score: 0.35

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25313505

Sources:
DTC TTD

DTC: NVP-AUY922
- Version: 02-September-2020
Alternate Names:

CHEMBL252164 ChEMBL Drug ID

Drug Info:

Publications:

Chen D et al., 2014, Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors., Eur J Med Chem
CIViC: LUMINESPIB
- Version: 14-September-2020
Alternate Names:

Drug Info:

Publications:

Shaw et al., 2016, Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F., N. Engl. J. Med.
GuideToPharmacology: 315661336
- Version: 29-September-2020
Alternate Names:

LUMINESPIB GuideToPharmacology Ligand Name

Drug Info:

Publications:
TTD: NVP-AUY922
- Version: 2020.06.01
Alternate Names:

D05BYA TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL252164
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Direct Interaction?	False
Endogenous Drug?	False
Specific Action of the Ligand	Inhibition

LUMINESPIB Drug Record

LUMINESPIB chembl:CHEMBL252164

Alternate Names:

Drug Info:

Publications:

LUMINESPIB TRAP1

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Inhibition

PMIDs: None found

Sources: GuideToPharmacology

LUMINESPIB ALK

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26698910

Sources: CIViC

LUMINESPIB HSP90AB1

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False

PMIDs: None found

Sources: GuideToPharmacology

LUMINESPIB HSP90AA1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 25313505

Sources: DTC TTD

DTC: NVP-AUY922

Alternate Names: CHEMBL252164 ChEMBL Drug ID

Drug Info:

Publications: Chen D et al., 2014, Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors., Eur J Med Chem

CIViC: LUMINESPIB

Alternate Names:

Drug Info:

Publications: Shaw et al., 2016, Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F., N. Engl. J. Med.

GuideToPharmacology: 315661336

Alternate Names: LUMINESPIB GuideToPharmacology Ligand Name

Drug Info:

Publications:

TTD: NVP-AUY922

Alternate Names: D05BYA TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL252164

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Inhibition

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
26698910

Sources:
CIViC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
25313505

Sources:
DTC TTD

Alternate Names:

CHEMBL252164 ChEMBL Drug ID

Publications:

Chen D et al., 2014, Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors., Eur J Med Chem

Publications:

Shaw et al., 2016, Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F., N. Engl. J. Med.

Alternate Names:

LUMINESPIB GuideToPharmacology Ligand Name

Alternate Names:

D05BYA TTD Drug ID