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LUSUTROMBOPAG Drug Record

  • Summary
  • Interactions
  • Claims
  • LUSUTROMBOPAG chembl:CHEMBL2107831 Approved

    Alternate Names:

    MULPLETA
    LUSUTROMBOPAG
    S-888711
    drugbank:13125
    chemidplus:1110766-97-6
    pubchem.compound:49843517
    chembl:CHEMBL2107831

    Drug Info:

    (1 More Sources)

    Publications:

    Li X et al., 2012, Defective regulatory B-cell compartment in patients with immune thrombocytopenia., Blood
    Kim ES, 2016, Lusutrombopag: First Global Approval., Drugs
    Yoshida H et al., 2018, Development of a new knock-in mouse model and evaluation of pharmacological activities of lusutrombopag, a novel, nonpeptidyl small-molecule agonist of the human thrombopoietin receptor c-Mpl., Exp Hematol
  • LUSUTROMBOPAG   MPL

    Interaction Score: 3.75

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:

    PMIDs:
    22859611 26666417 29274361


    Sources:
    TTD

  • LUSUTROMBOPAG   PROS1

    Interaction Score: 3.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • LUSUTROMBOPAG   F5

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • LUSUTROMBOPAG   PROC

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • LUSUTROMBOPAG   SERPINC1

    Interaction Score: 0.9

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • LUSUTROMBOPAG   F2

    Interaction Score: 0.71

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • TTD: S-888711

    • Version: 2020.06.01

    Alternate Names:
    D02MNR TTD Drug ID

    Drug Info:

    Publications:
    Li X et al., 2012, Defective regulatory B-cell compartment in patients with immune thrombocytopenia., Blood

  • TTD: Lusutrombopag

    • Version: 2020.06.01

    Alternate Names:
    D0TD1R TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL2107831

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • PharmGKB: lusutrombopag

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:

  • FDA: Lusutrombopag

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21