• Interaction Score: 2.55

    Interaction Types & Directionality:
    antagonist (inhibitory)
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name AGI-004, mecamylamine transdermal patch, CR
    Novel drug target Established target
    Trial Name mecamylamine HCl , TC-5231

  • Interaction Score: 2.13

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction α6/α3β2β3 chimera
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.47

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction α4β4
    Endogenous Drug? False

    PMIDs:
    14645658


  • Interaction Score: 0.32

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction α3β4
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.32

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Details of Interaction (&alpha;1)<sub>2</sub>&beta;1&delta;&epsilon;

    PMIDs:
    None found


  • Interaction Score: 0.29

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Details of Interaction (&alpha;7)<sub>5</sub>

    PMIDs:
    10082212


  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC