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METHYLTESTOSTERONE Drug Record

  • Summary
  • Interactions
  • Claims
  • METHYLTESTOSTERONE chembl:CHEMBL1395 ApprovedAntineoplastic

    Alternate Names:

    17-METHYLTESTOSTERONE
    ANDROID 25
    ORETON
    U-2842
    RU 24400
    L-589372
    NSC-9701
    NSC-139965
    PLEX HORMONE
    ANDROID 10
    TESTRED
    L 589.372
    METHITEST
    RU-24400
    ANDROID 5
    METHYLTESTOSTERONE
    PERANDREN
    TESTOVIS
    METHYLTESTOSTERONE CIII
    ORETON METHYL
    METANDREN
    CDB-110
    POTENSAN FTE
    L-589.372
    VIRILON
    17-BETA-HYDROXY-17-METHYLANDROST-4-EN-3-ONE
    17Α-METHYL-Δ4-ANDROSTEN-17Β-OL-3-ONE
    17BETA-HYDROXY-17-METHYLANDROST-4-EN-3-ONE
    17ALPHA-METHYLTESTOSTERONE
    17ALPHA-METHYL-DELTA(4)-ANDROSTEN-17BETA-OL-3-ONE
    4-ANDROSTENE-17ALPHA-METHYL-17BETA-OL-3-ONE
    17Α-METHYLTESTOSTERONE
    METILTESTOSTERONA
    17ALPHA-METHYL-3-OXO-4-ANDROSTEN-17BETA-OL
    17(ALPHA)-METHYL-DELTA(4)-ANDROSTEN-17(BETA)-OL-3-ONE
    METHYLTESTOSTERONUM
    drugbank:06710
    chemidplus:58-18-4
    rxcui:6904
    chembl:CHEMBL1395
    pubchem.compound:6010

    Drug Info:

    FDA Approval approved
    Drug Class Small molecule
    Drug Indications for treatment of dysfunctional libido in women
    (1 More Sources)

    Publications:

    Small et al., 2006, The case for secondary hormonal therapies in the chemotherapy age., J. Urol.
    Maudsley et al., 2006, Gonadotropin-releasing hormone functionally antagonizes testosterone activation of the human androgen receptor in prostate cells through focal adhesion complexes involving Hic-5., Neuroendocrinology
    Petraki et al., 2007, Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma., Histol. Histopathol.
    Omwancha et al., 2006, Selective androgen receptor modulators: in pursuit of tissue-selective androgens., Curr Opin Investig Drugs
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Lapauw et al., 2007, Is the effect of testosterone on body composition modulated by the androgen receptor gene CAG repeat polymorphism in elderly men?, Eur. J. Endocrinol.
    Ren et al., 2005, [Effects of glycosides of Tripterygium wilfordii, methyltestosterone and zhuanggushenjin capsule on nitric oxide synthase in rat testes]., Zhonghua Nan Ke Xue
    Huang R et al., 2014, Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway., Sci Rep
  • METHYLTESTOSTERONE   NOS1

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15934456


    Sources:
    NCI

  • METHYLTESTOSTERONE   RORC

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLTESTOSTERONE   AR

    Interaction Score: 0.13

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Trial Name methyltestosterone
    Novel drug target Established target
    Mechanism of Interaction Androgen Receptor agonist

    PMIDs:
    17084172 17202804 17128417 17086931 11752352 17322500


    Sources:
    DTC TdgClinicalTrial ChemblInteractions

  • METHYLTESTOSTERONE   ESR1

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25012808


    Sources:
    DTC

  • METHYLTESTOSTERONE   NR3C1

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TdgClinicalTrial: METHYLTESTOSTERONE

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications for treatment of dysfunctional libido in women
    Drug Class Small molecule
    FDA Approval approved

    Publications:

  • NCI: METHYLTESTOSTERONE

    • Version: 14-September-2017

    Alternate Names:
    C648 NCI drug code

    Drug Info:

    Publications:
    Ren et al., 2005, [Effects of glycosides of Tripterygium wilfordii, methyltestosterone and zhuanggushenjin capsule on nitric oxide synthase in rat testes]., Zhonghua Nan Ke Xue

  • DTC: METHYLTESTOSTERONE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1395 ChEMBL Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1395

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL1395

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21