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MEXAZOLAM Drug Record

  • Summary
  • Interactions
  • Claims
  • MEXAZOLAM chembl:CHEMBL1743261

    Alternate Names:

    MEXAZOLAM

    Drug Info:

    Drug Type small molecule
    Drug Groups experimental
    Drug Categories benzazepines
    Drug Categories benzodiazepines and benzodiazepine derivatives
    Drug Categories central nervous system depressants
    Drug Categories cytochrome p-450 cyp3a substrates
    Drug Categories cytochrome p-450 cyp3a4 substrates
    Drug Categories cytochrome p-450 substrates
    Drug Categories heterocyclic compounds, fused-ring
    (0 More Sources)

    Publications:

    Fernandes H et al., 2014, Mexazolam: clinical efficacy and tolerability in the treatment of anxiety., Neurol Ther
    Zhu S et al., 2018, Structure of a human synaptic GABA<sub>A</sub> receptor., Nature
    Sigel E et al., 2012, Structure, function, and modulation of GABA(A) receptors., J Biol Chem
  • MEXAZOLAM   GABRA1

    Interaction Score: 1.76

    Interaction Types & Directionality:
    ligand
    positive modulator (activating)

    Interaction Info:

    PMIDs:
    26000220 29950725 23038269


    Sources:
    DrugBank

  • DrugBank: DB15489

    • Version: 5.1.7

    Alternate Names:
    MEXAZOLAM DrugBank Drug Name
    31868-18-5 CAS Number
    Melex Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups experimental
    Drug Categories benzazepines

    Publications:
    Fernandes H et al., 2014, Mexazolam: clinical efficacy and tolerability in the treatment of anxiety., Neurol Ther
    Zhu S et al., 2018, Structure of a human synaptic GABA<sub>A</sub> receptor., Nature
    Sigel E et al., 2012, Structure, function, and modulation of GABA(A) receptors., J Biol Chem

  • ChemblDrugs: chembl:CHEMBL1743261

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2021-04-13