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MIDOMAFETAMINE Drug Record

  • Summary
  • Interactions
  • Claims
  • MIDOMAFETAMINE chembl:CHEMBL43048

    Alternate Names:

    METHYLENEDIOXY METHAMPHETAMINE
    MIDOMAFETAMINE
    METHYLENEDIOXYMETHAMPHETAMINE
    3,4-METHYLENEDIOXYMETHAMPHETAMINE
    MDMA

    Drug Info:

    (0 More Sources)

    Publications:

    Biezonski et al., 2010, Effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity., J. Neurochem.
    Hansen et al., 2002, Methylenedioxymethamphetamine decreases plasmalemmal and vesicular dopamine transport: mechanisms and implications for neurotoxicity., J. Pharmacol. Exp. Ther.
    Nash et al., 1994, Effect of the R(-) and S(+) isomers of MDA and MDMA on phosphatidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors., Neurosci. Lett.
    Lyon et al., 1986, 3,4-Methylenedioxymethamphetamine (MDMA): stereoselective interactions at brain 5-HT1 and 5-HT2 receptors., Psychopharmacology (Berl.)
    Fitzgerald et al., 1990, Effects of methylenedioxymethamphetamine on the release of monoamines from rat brain slices., Eur. J. Pharmacol.
    Fleckenstein et al., 2007, New insights into the mechanism of action of amphetamines., Annu. Rev. Pharmacol. Toxicol.
  • MIDOMAFETAMINE   SLC18A2

    Interaction Score: 1.95

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    20002520 11861820


    Sources:
    TTD

  • MIDOMAFETAMINE   HTR2B

    Interaction Score: 1.45

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:

    PMIDs:
    2871581


    Sources:
    TTD

  • MIDOMAFETAMINE   SLC6A3

    Interaction Score: 0.97

    Interaction Types & Directionality:
    negative modulator (inhibitory)

    Interaction Info:

    PMIDs:
    11861820 1982265 17209801


    Sources:
    TTD

  • MIDOMAFETAMINE   HTR2C

    Interaction Score: 0.74

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:

    PMIDs:
    7824160 2871581


    Sources:
    TTD

  • MIDOMAFETAMINE   HTR2A

    Interaction Score: 0.37

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:

    PMIDs:
    7824160 2871581


    Sources:
    TTD

  • TTD: METHYLENEDIOXYMETHAMPHETAMINE

    • Version: 2020.06.01

    Alternate Names:
    D0F5NJ TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL43048

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21