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MILTEFOSINE Drug Record

  • Summary
  • Interactions
  • Claims
  • MILTEFOSINE chembl:CHEMBL125 ApprovedAntineoplastic

    Alternate Names:

    NSC-605583
    MILTEX
    D-18506
    IMPAVIDO
    HDPC
    MILTEFOSINE
    HEXADECYL 2-(TRIMETHYLAZANIUMYL)ETHYL PHOSPHATE
    HEXADECYLPHOSPHORYLCHOLINE
    MILTEFOSINA
    MONOHEXADECYLPHOSPHOCHOLINE
    MILTÉFOSINE
    MILTEFOSIN
    MONOHEXADECYLPHOSPHORYLCHOLINE
    HEXADECYLPHOSPHOCHOLINE
    rxcui:1494066
    pubchem.compound:3599
    chemidplus:58066-85-6
    chembl:CHEMBL125
    drugbank:09031

    Drug Info:

    (0 More Sources)

    Publications:

    Hochhuth et al., 1992, Hexadecylphosphocholine induces interferon-gamma secretion and expression of GM-CSF mRNA in human mononuclear cells., Cell. Immunol.
    Rybczynska et al., 2001, MDR1 causes resistance to the antitumour drug miltefosine., Br. J. Cancer
    Zeisig et al., 1995, Influence of hexadecylphosphocholine on the release of tumor necrosis factor and nitroxide from peritoneal macrophages in vitro., J. Cancer Res. Clin. Oncol.
    Verma et al., 2006, The anti-leishmanial drug miltefosine causes insulin resistance in skeletal muscle cells in vitro., Diabetologia
  • MILTEFOSINE   CSF2

    Interaction Score: 0.6

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1555249


    Sources:
    NCI

  • MILTEFOSINE   PLA2G1B

    Interaction Score: 0.56

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • MILTEFOSINE   TNF

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7883777


    Sources:
    NCI

  • MILTEFOSINE   PIK3CA

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16752184


    Sources:
    NCI

  • MILTEFOSINE   ABCB1

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11355955


    Sources:
    NCI

  • NCI: HEXADECYLPHOSPHOCHOLINE

    • Version: 14-September-2017

    Alternate Names:
    C1170 NCI drug code

    Drug Info:

    Publications:
    Hochhuth et al., 1992, Hexadecylphosphocholine induces interferon-gamma secretion and expression of GM-CSF mRNA in human mononuclear cells., Cell. Immunol.
    Zeisig et al., 1995, Influence of hexadecylphosphocholine on the release of tumor necrosis factor and nitroxide from peritoneal macrophages in vitro., J. Cancer Res. Clin. Oncol.

  • NCI: MILTEFOSINE

    • Version: 14-September-2017

    Alternate Names:
    C1170 NCI drug code

    Drug Info:

    Publications:
    Verma et al., 2006, The anti-leishmanial drug miltefosine causes insulin resistance in skeletal muscle cells in vitro., Diabetologia
    Rybczynska et al., 2001, MDR1 causes resistance to the antitumour drug miltefosine., Br. J. Cancer

  • TTD: Miltefosine

    • Version: 2020.06.01

    Alternate Names:
    D00FGR TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL125

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21