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MOXONIDINE Drug Record

  • Summary
  • Interactions
  • Claims
  • MOXONIDINE chembl:CHEMBL19236 Approved

    Alternate Names:

    BE-5895
    LY-326869
    FISIOTENS
    MOXONIDINE
    BDF-5896
    NORCYNT
    CYNT
    NUCYNT
    LY326869
    NORMATENS
    BDF5896
    PHYSIOTENS
    BE5895
    (2R,4R)-1-[(2S)-5-[(AMINOIMINOMETHYL)AMINO]-1-OXO-2-[[(1,2,3,4-TETRAHYDRO-3-METHYL-8- QUINOLINYL)SULFONYL]AMINO]PENTYL]-4-METHYL-2-PIPERIDINECARBOXYLIC ACID
    rxcui:30257
    pubchem.compound:4810
    chembl:CHEMBL19236
    chemidplus:75438-57-2
    drugbank:09242

    Drug Info:

    (0 More Sources)

    Publications:

    Vilardaga JP et al., 2005, Molecular basis of inverse agonism in a G protein-coupled receptor., Nat Chem Biol
    Stone LS et al., 2003, Moxonidine, a mixed alpha(2)-adrenergic and imidazoline receptor agonist, identifies a novel adrenergic target for spinal analgesia., Ann N Y Acad Sci
    Buccafusco JJ et al., 1995, Role of medullary I1-imidazoline and alpha 2-adrenergic receptors in the antihypertensive responses evoked by central administration of clonidine analogs in conscious spontaneously hypertensive rats., J Pharmacol Exp Ther
    Zhu QM et al., 1999, Cardiovascular effects of rilmenidine, moxonidine and clonidine in conscious wild-type and D79N alpha2A-adrenoceptor transgenic mice., Br J Pharmacol
  • MOXONIDINE   ADRA2A

    Interaction Score: 1.74

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:

    PMIDs:
    16407989 15028616 7791087 10217548


    Sources:
    DTC TTD

  • MOXONIDINE   ADRA2B

    Interaction Score: 0.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • MOXONIDINE   ADRA2C

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • DTC: MOXONIDINE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL19236 ChEMBL Drug ID

    Drug Info:

    Publications:
    Vilardaga JP et al., 2005, Molecular basis of inverse agonism in a G protein-coupled receptor., Nat Chem Biol

  • TTD: MOXONIDINE

    • Version: 2020.06.01

    Alternate Names:
    D0E9PK TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL19236

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21