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MURAGLITAZAR Drug Record

  • Summary
  • Interactions
  • Claims
  • MURAGLITAZAR chembl:CHEMBL186179

    Alternate Names:

    MK0478
    BMS-298585
    MK-0478
    MURAGLITAZAR
    BMS-298585-01

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications antidiabetic
    (2 More Sources)

    Publications:

    Geese WJ et al., 2008, Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor gamma agonists., Pharmacogenet Genomics
  • MURAGLITAZAR   REN

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18794727


    Sources:
    PharmGKB

  • MURAGLITAZAR   EDN1

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18794727


    Sources:
    PharmGKB

  • MURAGLITAZAR   PPARA

    Interaction Score: 0.54

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Trial Name muraglitazar, BMS-298585
    Novel drug target Established target
    Mechanism of Interaction Peroxisome proliferator-activated receptor alpha agonist

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions TTD

  • MURAGLITAZAR   PPARG

    Interaction Score: 0.26

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Peroxisome proliferator-activated receptor gamma agonist
    Direct Interaction yes
    Trial Name muraglitazar, BMS-298585

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions TTD

  • MURAGLITAZAR   ADRB1

    Interaction Score: 0.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18794727


    Sources:
    PharmGKB

  • MURAGLITAZAR   PPARD

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TdgClinicalTrial: MURAGLITAZAR

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antidiabetic
    Drug Class Small molecule
    FDA Approval not approved

    Publications:

  • PharmGKB: muraglitazar

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Geese WJ et al., 2008, Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor gamma agonists., Pharmacogenet Genomics

  • TTD: MURAGLITAZAR

    • Version: 2020.06.01

    Alternate Names:
    D0M3UT TTD Drug ID

    Drug Info:

    Publications:

  • DTC: MURAGLITAZAR

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL186179 ChEMBL Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL186179

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL186179

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21