DGIdb - NOCODAZOLE Drug Record

NOCODAZOLE chembl:CHEMBL9514 Antineoplastic

Alternate Names:

NOCODAZOLE
R-17934
ONCODAZOLE
R17,934
ONCOBENDAZOLE
METHYL N-(5-THENOYL-2-BENZIMIDAZOLYL)CARBAMATE
(5-(2-THIENYLCARBONYL)-1H-BENZIMIDAZOL-2-YL)-CARBAMIC ACID METHYL ESTER
METHYL (5-(2-THIENYLCARBONYL))-1H-BENZIMIDAZOLE-2-YLCARBAMATE
N-(5-(2-THENOYL)-2-BENZIMIDAZOLYL)CARBAMIC ACID METHYL ESTER
R 17934
N-(5-(2-THIENOYL)-2-BENZIMIDAZOLYL)CARBAMIC ACID METHYL ESTER
pubchem.compound:4122
chemidplus:31430-18-9
drugbank:08313
chembl:CHEMBL9514

Drug Info:

Drug Categories	heterocyclic compounds, fused-ring

(0 More Sources)

Publications:

Kamal A et al., 2011, Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents., Eur J Med Chem
Kuroiwa K et al., 2015, Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents., ACS Med Chem Lett
O'Boyle NM et al., 2014, β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand., J Med Chem
Guan Q et al., 2014, Synthesis and evaluation of benzimidazole carbamates bearing indole moieties for antiproliferative and antitubulin activities., Eur J Med Chem
Kumar AS et al., 2013, Design and synthesis of biaryl aryl stilbenes/ethylenes as antimicrotubule agents., Eur J Med Chem
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Yi X et al., 2012, Identification of a class of novel tubulin inhibitors., J Med Chem

NOCODAZOLE TUBB4A

Interaction Score: 0.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBA3C

Interaction Score: 0.55

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE HPGDS

Interaction Score: 0.41

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
NOCODAZOLE TUBA3E

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBB2B

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBA3D

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBB8

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBB6

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBA1B

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBA1C

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBB2A

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBA4A

Interaction Score: 0.31

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBB3

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBB4B

Interaction Score: 0.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBA1A

Interaction Score: 0.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBB1

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE TUBB

Interaction Score: 0.23

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC
NOCODAZOLE NR0B1

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NOCODAZOLE HSPB1

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22435708

Sources:
DTC
NOCODAZOLE CREBBP

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NOCODAZOLE ATAD5

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NOCODAZOLE GMNN

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NOCODAZOLE CYP1A2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NOCODAZOLE NFE2L2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NOCODAZOLE AR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DrugBank: DB08313
- Version: 5.1.7
Alternate Names:

NOCODAZOLE DrugBank Drug Name

31430-18-9 CAS Number

CHEMBL9514 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Categories antimitotic agents

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

DTC: NOCODAZOLE

Version: 02-September-2020

Alternate Names:

CHEMBL9514 ChEMBL Drug ID

Drug Info:

Publications:

Kamal A et al., 2011, Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents., Eur J Med Chem

Kuroiwa K et al., 2015, Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents., ACS Med Chem Lett

O'Boyle NM et al., 2014, β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand., J Med Chem

ChemblDrugs: chembl:CHEMBL9514
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

NOCODAZOLE	DrugBank Drug Name
31430-18-9	CAS Number
CHEMBL9514	ChEMBL ID

Drug Type	small molecule
Drug Groups	experimental
Drug Categories	antimitotic agents

NOCODAZOLE Drug Record

NOCODAZOLE chembl:CHEMBL9514 Antineoplastic

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21194809 25815147 25369367 25262051 23313639

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22435708

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21194809 25815147 25369367 25262051 23313639

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22435708

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

NOCODAZOLE DrugBank Drug Name

31430-18-9 CAS Number

CHEMBL9514 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Categories antimitotic agents

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Alternate Names:

CHEMBL9514 ChEMBL Drug ID