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NOCODAZOLE Drug Record

  • Summary
  • Interactions
  • Claims
  • NOCODAZOLE chembl:CHEMBL9514 Antineoplastic

    Alternate Names:

    NOCODAZOLE
    R-17934
    ONCODAZOLE
    R17,934
    ONCOBENDAZOLE
    METHYL N-(5-THENOYL-2-BENZIMIDAZOLYL)CARBAMATE
    (5-(2-THIENYLCARBONYL)-1H-BENZIMIDAZOL-2-YL)-CARBAMIC ACID METHYL ESTER
    METHYL (5-(2-THIENYLCARBONYL))-1H-BENZIMIDAZOLE-2-YLCARBAMATE
    N-(5-(2-THENOYL)-2-BENZIMIDAZOLYL)CARBAMIC ACID METHYL ESTER
    R 17934
    N-(5-(2-THIENOYL)-2-BENZIMIDAZOLYL)CARBAMIC ACID METHYL ESTER
    pubchem.compound:4122
    chemidplus:31430-18-9
    drugbank:08313
    chembl:CHEMBL9514

    Drug Info:

    (0 More Sources)

    Publications:

    O'Boyle NM et al., 2014, β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand., J Med Chem
    Kamal A et al., 2011, Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents., Eur J Med Chem
    Kuroiwa K et al., 2015, Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents., ACS Med Chem Lett
    Kumar AS et al., 2013, Design and synthesis of biaryl aryl stilbenes/ethylenes as antimicrotubule agents., Eur J Med Chem
    Guan Q et al., 2014, Synthesis and evaluation of benzimidazole carbamates bearing indole moieties for antiproliferative and antitubulin activities., Eur J Med Chem
    Yi X et al., 2012, Identification of a class of novel tubulin inhibitors., J Med Chem
  • NOCODAZOLE   TUBA3C

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB4A

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBA3E

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBA1B

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBA1C

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB6

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB2B

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBA4A

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBA3D

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB8

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB3

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB2A

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBA1A

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB4B

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   TUBB1

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25369367 21194809 25815147 23313639 25262051


    Sources:
    DTC

  • NOCODAZOLE   NR0B1

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NOCODAZOLE   HSPB1

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22435708


    Sources:
    DTC

  • NOCODAZOLE   CREBBP

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NOCODAZOLE   ATAD5

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NOCODAZOLE   GMNN

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NOCODAZOLE   CYP1A2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NOCODAZOLE   NFE2L2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NOCODAZOLE   AR

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DTC: NOCODAZOLE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL9514 ChEMBL Drug ID

    Drug Info:

    Publications:
    Kamal A et al., 2011, Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents., Eur J Med Chem
    Kuroiwa K et al., 2015, Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents., ACS Med Chem Lett
    O'Boyle NM et al., 2014, β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand., J Med Chem

  • ChemblDrugs: chembl:CHEMBL9514

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21