• Interaction Score: 6.38

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand None

    PMIDs:
    None found


  • Interaction Score: 3.19

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Norgestimate-induced inhibition of hTRPC6-mediated Ca2+ entry in transfected HEK-FITR cells stimulated with the OAG diacylglycerol analog.
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 2.05

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Progesterone receptor agonist
    Direct Interaction yes
    Novel drug target Established target

  • Interaction Score: 0.38

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Novel drug target Established target
    Trial Name -

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    partial agonist (activating)

    Interaction Info:

    PMIDs:
    15625768


    Sources:
    DTC

    • Version: 01-August-2011

    Alternate Names:
    NORGESTIMATE Primary Drug Name

    Drug Info:
    Year of Approval 1989
    Drug Class contraceptives, oral, synthetic

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Contraceptives, Oral, Synthetic
    Drug Class small molecule
    FDA Approval 1989

    Publications:

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1200934 ChEMBL Drug ID

    Drug Info:

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    D09QZI TTD Drug ID

    Drug Info:

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    NORGESTIMATE GuideToPharmacology Ligand Name

    Drug Info:

    Publications:

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications: