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OFLOXACIN Drug Record

  • Summary
  • Interactions
  • Claims
  • OFLOXACIN chembl:CHEMBL4 ApprovedAntineoplastic

    Alternate Names:

    OFLOXACIN
    FLOXIN
    TARIVID 400
    FLOXIN OTIC
    TARIVID
    TARIVID I.V.
    HOE-280
    VISIREN
    DL-8280
    OCUFLOX
    J01MA01
    EXOCIN

    Drug Info:

    (1 More Sources)

    Publications:

    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Roche et al., 1988, Interleukin-1 production by antibiotic-treated human monocytes., J. Antimicrob. Chemother.
    Terashi et al., 2000, Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells., Antimicrob. Agents Chemother.
    Biglino et al., 1990, Effects of ofloxacin on cell-mediated immune response and lymphokine production., J. Antimicrob. Chemother.
    Erat et al., 2003, In vitro effects of some antibiotics on glutathione reductase from sheep liver., J Enzyme Inhib Med Chem
  • OFLOXACIN   GSR

    Interaction Score: 0.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15008519


    Sources:
    NCI

  • OFLOXACIN   IL2

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2115511


    Sources:
    NCI

  • OFLOXACIN   IL1B

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3260587


    Sources:
    NCI

  • OFLOXACIN   ABCC1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10817732


    Sources:
    NCI

  • OFLOXACIN   G6PD

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • OFLOXACIN   CYP2C9

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • OFLOXACIN   CYP2C19

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • OFLOXACIN   CYP1A2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • OFLOXACIN   CYP2D6

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • OFLOXACIN   HSD17B10

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • OFLOXACIN   CYP3A4

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • DTC: OFLOXACIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL4 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

  • NCI: OFLOXACIN

    • Version: 14-September-2017

    Alternate Names:
    C712 NCI drug code

    Drug Info:

    Publications:
    Roche et al., 1988, Interleukin-1 production by antibiotic-treated human monocytes., J. Antimicrob. Chemother.
    Terashi et al., 2000, Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells., Antimicrob. Agents Chemother.
    Erat et al., 2003, In vitro effects of some antibiotics on glutathione reductase from sheep liver., J Enzyme Inhib Med Chem

  • TTD: Ofloxacin

    • Version: 2020.06.01

    Alternate Names:
    D03NHW TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL4

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • PharmGKB: ofloxacin

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21