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PEGAPTANIB SODIUM Drug Record

  • Summary
  • Interactions
  • Claims
  • PEGAPTANIB SODIUM chembl:CHEMBL1201421 Approved

    Alternate Names:

    NX1838
    MACUGEN
    PEGAPTANIB SODIUM
    NX-1838
    EYEOO1
    EYE001
    EYE-001
    PEGAPTANIB OCTASODIUM
    EYE 001
    NX 1838
    pubchem.compound:24847876
    chemidplus:222716-86-1
    drugbank:04895
    chembl:CHEMBL1201421
    rxcui:498509

    Drug Info:

    FDA Approval approved
    Drug Class aptamer
    Drug Indications for treatment of age-related macular degeneration
    Drug Class treatment for age-related macular degeneration, amd
    Year of Approval 2004
    (2 More Sources)

    Publications:

    Vinores, 2006, Pegaptanib in the treatment of wet, age-related macular degeneration., Int J Nanomedicine
    Miyake M et al., 2014, Vascular endothelial growth factor gene and the response to anti-vascular endothelial growth factor treatment for choroidal neovascularization in high myopia., Ophthalmology
  • PEGAPTANIB SODIUM   NRP1

    Interaction Score: 30.91

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17717967


    Sources:
    TEND TTD

  • PEGAPTANIB SODIUM   VEGFA

    Interaction Score: 3.25

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name Macugen
    Novel drug target Established target
    Mechanism of Interaction Vascular endothelial growth factor A antagonist

    PMIDs:
    23953100


    Sources:
    TdgClinicalTrial ChemblInteractions PharmGKB

  • TEND: PEGAPTANIB

    • Version: 01-August-2011

    Alternate Names:
    PEGAPTANIB Primary Drug Name

    Drug Info:
    Year of Approval 2004
    Drug Class treatment for age-related macular degeneration, amd

    Publications:

  • TdgClinicalTrial: PEGAPTANIB

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications for treatment of age-related macular degeneration
    Drug Class aptamer
    FDA Approval approved

    Publications:

  • PharmGKB: pegaptanib

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Miyake M et al., 2014, Vascular endothelial growth factor gene and the response to anti-vascular endothelial growth factor treatment for choroidal neovascularization in high myopia., Ophthalmology

  • TTD: Pegaptanib

    • Version: 2020.06.01

    Alternate Names:
    D0UF9W TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1201421

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL1201421

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21