PENTOBARBITAL CALCIUM |
NSC-28708 |
NEMBUTAL |
MEBUMAL |
MEBUBARBITAL |
PENTOBARBITAL CII |
PENTOBARBITAL |
PENTOBARBITAL SODIUM |
NSC 28708 |
NEMBUTAL® |
5-ETHYL-5-(1-METHYLBUTYL)BARBITURIC ACID |
PENTOBARBITONE |
5-ETHYL-5-(SEC-PENTYL)BARBITURIC ACID |
PENTOBARBITURIC ACID |
5-ETHYL-5-(1-METHYL-BUTYL)-PYRIMIDINE-2,4,6-TRIONE |
(RS)-PENTOBARBITAL |
5-ETHYL-5-(1-METHYLBUTYL)-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE |
(±)-PENTOBARBITAL |
pubchem.compound:4737 |
chemidplus:76-74-4 |
chembl:CHEMBL448 |
drugbank:00312 |
rxcui:8004 |
FDA Approval | Approved before 1982 |
Drug Class | small molecule |
Drug Indications | Hypnotics and Sedatives |
Year of Approval | approved before 1982 |
Drug Class | hypnotics and sedatives |
Drug Categories | cytochrome p-450 cyp2a6 inducers (strong) |
Drug Groups | investigational |
Drug Categories | anticholinergic agents |
Drug Categories | anticonvulsants |
Drug Categories | cytochrome p-450 cyp3a inducers (strong) |
Drug Categories | cytochrome p-450 cyp3a4 inducers |
Drug Categories | cytochrome p-450 enzyme inducers |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | drugs that are mainly renally excreted |
Drug Categories | nicotinic antagonists |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
positive modulator (activating) |
potentiator |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Trial Name | - |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
positive modulator (activating) |
potentiator |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
Trial Name | - |
positive modulator (activating) |
potentiator |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
Trial Name | - |
positive modulator (activating) |
potentiator |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
Trial Name | - |
positive modulator (activating) |
potentiator |
Trial Name | - |
Novel drug target | Established target |
Direct Interaction | yes |
positive modulator (activating) |
potentiator |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
Trial Name | - |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
PENTOBARBITAL | DrugBank Drug Name |
76-74-4 | CAS Number |
Cafergot Pb Sup | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Groups | investigational |
PENTOBARBITAL | Primary Drug Name |
Drug Class | hypnotics and sedatives |
Year of Approval | approved before 1982 |
Drug Indications | Hypnotics and Sedatives |
Drug Class | small molecule |
FDA Approval | Approved before 1982 |
D0F0YZ | TTD Drug ID |