DGIdb - PERICIAZINE Drug Record

PERICIAZINE chembl:CHEMBL251940 Approved

Alternate Names:

RP-8909
PERICYAZINE
SKF-20716
PROPERICIAZINE
PERICIAZINE
NEULACTIL
CYANO-3 ((HYDROXY-4 PIPERIDYL-1)-3 PROPYL)-10 PHENOTHIAZINE
2-CYANO-10-(3-(4-HYDROXYPIPERIDINO)PROPYL)PHENOTHIAZINE
PERICIAZINUM
2-CYANO-10-(3-(4-HYDROXY-1-PIPERIDYL)PROPYL)PHENOTHIAZINE
10-(3-(4-HYDROXYPIPERIDINO)PROPYL)PHENOTHIAZINE-2-CARBONITRILE
PERICIAZINA
PIPEROCYANOMAZINE
drugbank:01608
chemidplus:2622-26-6
rxcui:8766
pubchem.compound:4747
chembl:CHEMBL251940

Drug Info:

FDA Approval	not approved by the FDA
Drug Class	small molecule
Drug Indications	Antipsychotic Agents
Drug Class	antipsychotic agents
Year of Approval	not approved by the fda

(1 More Sources)

Publications:

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Bisson WH et al., 2007, Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs., Proc Natl Acad Sci U S A

PERICIAZINE ADRA1B

Interaction Score: 1.55

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17016423 17139284 11752352

Sources:
TdgClinicalTrial TEND TTD
PERICIAZINE ADRA1D

Interaction Score: 1.19

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TEND
PERICIAZINE ADRA1A

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TEND
PERICIAZINE AR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17606915

Sources:
DTC

TEND: PROPERICIAZINE
- Version: 01-August-2011
Alternate Names:

PROPERICIAZINE Primary Drug Name

Drug Info:

Year of Approval not approved by the fda

Drug Class antipsychotic agents

Publications:
TdgClinicalTrial: PROPERICIAZINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Antipsychotic Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Publications:
DTC: PERICIAZINE
- Version: 02-September-2020
Alternate Names:

CHEMBL251940 ChEMBL Drug ID

Drug Info:

Publications:

Bisson WH et al., 2007, Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs., Proc Natl Acad Sci U S A
TTD: Propericiazine
- Version: 2020.06.01
Alternate Names:

D00AWT TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL251940
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target

Trial Name	-
Novel drug target	Established target

Trial Name	-
Novel drug target	Established target

PERICIAZINE Drug Record

PERICIAZINE chembl:CHEMBL251940 Approved

Alternate Names:

Drug Info:

Publications:

PERICIAZINE ADRA1B

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 17016423 17139284 11752352

Sources: TdgClinicalTrial TEND TTD

PERICIAZINE ADRA1D

Interaction Types & Directionality: n/a

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial TEND

PERICIAZINE ADRA1A

Interaction Types & Directionality: n/a

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial TEND

PERICIAZINE AR

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17606915

Sources: DTC

TEND: PROPERICIAZINE

Alternate Names: PROPERICIAZINE Primary Drug Name

Drug Info: Year of Approval not approved by the fda Drug Class antipsychotic agents

Publications:

TdgClinicalTrial: PROPERICIAZINE

Alternate Names:

Drug Info: Drug Indications Antipsychotic Agents Drug Class small molecule FDA Approval not approved by the FDA

Publications:

DTC: PERICIAZINE

Alternate Names: CHEMBL251940 ChEMBL Drug ID

Drug Info:

Publications: Bisson WH et al., 2007, Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs., Proc Natl Acad Sci U S A

TTD: Propericiazine

Alternate Names: D00AWT TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL251940

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17016423 17139284 11752352

Sources:
TdgClinicalTrial TEND TTD

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

n/a

PMIDs:
17606915

Sources:
DTC

Alternate Names:

PROPERICIAZINE Primary Drug Name

Drug Info:

Year of Approval not approved by the fda

Drug Class antipsychotic agents

Drug Info:

Drug Indications Antipsychotic Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Alternate Names:

CHEMBL251940 ChEMBL Drug ID

Publications:

Bisson WH et al., 2007, Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs., Proc Natl Acad Sci U S A

Alternate Names:

D00AWT TTD Drug ID