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PHENETHYLISOTHIOCYANATE Drug Record

  • Summary
  • Interactions
  • Claims
  • PHENETHYLISOTHIOCYANATE chembl:CHEMBL151649 Antineoplastic

    Alternate Names:

    PHENETHYL ISOTHIOCYANATE
    PHENYLETHYL ISOTHIOCYANATE
    PHENETHYLISOTHIOCYANATE

    Drug Info:

    (0 More Sources)

    Publications:

    Cavell BE et al., 2012, Natural product-derived antitumor compound phenethyl isothiocyanate inhibits mTORC1 activity via TSC2., J Nat Prod
    Wang X et al., 2011, Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships., J Med Chem
    Terada Y et al., 2015, Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard., J Nat Prod
    Yoshigae Y et al., 2013, The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation., Drug Metab Dispos
  • PHENETHYLISOTHIOCYANATE   TRPA1

    Interaction Score: 1.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26263397


    Sources:
    DTC

  • PHENETHYLISOTHIOCYANATE   FKBP1A

    Interaction Score: 1.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22607231


    Sources:
    DTC

  • PHENETHYLISOTHIOCYANATE   CYP2E1

    Interaction Score: 0.67

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23371965


    Sources:
    DTC

  • PHENETHYLISOTHIOCYANATE   TRPV1

    Interaction Score: 0.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26263397


    Sources:
    DTC

  • PHENETHYLISOTHIOCYANATE   MAPK3

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22607231


    Sources:
    DTC

  • PHENETHYLISOTHIOCYANATE   MTOR

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22607231


    Sources:
    DTC

  • PHENETHYLISOTHIOCYANATE   MAPK1

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22607231


    Sources:
    DTC

  • PHENETHYLISOTHIOCYANATE   TP53

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21241062


    Sources:
    DTC

  • DTC: PHENETHYLISOTHIOCYANATE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL151649 ChEMBL Drug ID

    Drug Info:

    Publications:
    Yoshigae Y et al., 2013, The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation., Drug Metab Dispos
    Terada Y et al., 2015, Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard., J Nat Prod
    Wang X et al., 2011, Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships., J Med Chem

  • ChemblDrugs: chembl:CHEMBL151649

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21