DGIdb - PHENETHYLISOTHIOCYANATE Drug Record

PHENETHYLISOTHIOCYANATE chembl:CHEMBL151649 Antineoplastic

Alternate Names:

PHENETHYL ISOTHIOCYANATE
PHENYLETHYL ISOTHIOCYANATE
PHENETHYLISOTHIOCYANATE

Drug Info:

Drug Categories	toxic actions
Drug Categories	sulfur compounds
Drug Categories	protective agents
Drug Categories	noxae
Drug Categories	isocyanates
Drug Categories	enzyme inhibitors
Drug Categories	compounds used in a research, industrial, or household setting
Drug Categories	carcinogens
Drug Categories	antineoplastic agents
Drug Categories	anticarcinogenic agents
Drug Categories	aldehyde dehydrogenase, antagonists & inhibitors
Drug Groups	investigational
Drug Type	small molecule

(0 More Sources)

Publications:

Cavell BE et al., 2012, Natural product-derived antitumor compound phenethyl isothiocyanate inhibits mTORC1 activity via TSC2., J Nat Prod
Wang X et al., 2011, Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships., J Med Chem
Terada Y et al., 2015, Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard., J Nat Prod
Yoshigae Y et al., 2013, The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation., Drug Metab Dispos
Mi L et al., 2011, Identification of potential protein targets of isothiocyanates by proteomics., Chem Res Toxicol

PHENETHYLISOTHIOCYANATE FBXO41

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE CYB5B

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE SUCLG2

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE ATP5I

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE NUDC

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TPM4

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TPD52L2

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE YWHAH

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE UCHL1

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE HSPE1

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE ACTA2

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE SF3A3

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE HNRNPF

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE PAPPA

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE YWHAZ

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE USP14

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE YWHAQ

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE HSPH1

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE SMARCE1

Interaction Score: 2.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE YWHAB

Interaction Score: 1.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE S100A10

Interaction Score: 1.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE ATP5L

Interaction Score: 1.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE RANBP1

Interaction Score: 1.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE HNRNPK

Interaction Score: 1.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TPM1

Interaction Score: 1.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE YWHAE

Interaction Score: 0.71

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE ATP5B

Interaction Score: 0.71

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE ACTB

Interaction Score: 0.54

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE VCP

Interaction Score: 0.54

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TXN

Interaction Score: 0.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE PSMC3

Interaction Score: 0.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE VIM

Interaction Score: 0.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE DIABLO

Interaction Score: 0.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE PSMA3

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TPM3

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE MT-ND1

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE FKBP1A

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22607231

Sources:
DTC
PHENETHYLISOTHIOCYANATE CYP2E1

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23371965

Sources:
DTC
PHENETHYLISOTHIOCYANATE TUBA3C

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE HSPA4

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE HSPB1

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TRPA1

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26263397

Sources:
DTC
PHENETHYLISOTHIOCYANATE TUBB2A

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TUBA4A

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TUBB3

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE MAPK3

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22607231

Sources:
DTC
PHENETHYLISOTHIOCYANATE TUBB4B

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TUBA1A

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE TRPV1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26263397

Sources:
DTC
PHENETHYLISOTHIOCYANATE TUBB1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21838287

Sources:
DrugBank
PHENETHYLISOTHIOCYANATE MTOR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22607231

Sources:
DTC
PHENETHYLISOTHIOCYANATE MAPK1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22607231

Sources:
DTC
PHENETHYLISOTHIOCYANATE TP53

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21241062

Sources:
DTC

DrugBank: DB12695
- Version: 5.1.7
Alternate Names:

PHENETHYL ISOTHIOCYANATE DrugBank Drug Name

2257-09-2 CAS Number

CHEMBL151649 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups investigational

Drug Categories aldehyde dehydrogenase, antagonists & inhibitors

Publications:

Mi L et al., 2011, Identification of potential protein targets of isothiocyanates by proteomics., Chem Res Toxicol

DTC: PHENETHYLISOTHIOCYANATE

Version: 02-September-2020

Alternate Names:

CHEMBL151649 ChEMBL Drug ID

Drug Info:

Publications:

Yoshigae Y et al., 2013, The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation., Drug Metab Dispos

Terada Y et al., 2015, Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard., J Nat Prod

Wang X et al., 2011, Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships., J Med Chem

ChemblDrugs: chembl:CHEMBL151649
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

PHENETHYL ISOTHIOCYANATE	DrugBank Drug Name
2257-09-2	CAS Number
CHEMBL151649	ChEMBL ID

PHENETHYLISOTHIOCYANATE Drug Record

PHENETHYLISOTHIOCYANATE chembl:CHEMBL151649 Antineoplastic

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21838287

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
21838287