• Interaction Score: 1.7

    Interaction Types & Directionality:
    inverse agonist (inhibitory)
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Histamine H3 receptor inverse agonist
    Details of the Assay for Interaction Measured in a [<sup>125</sup>I]iodoproxyfan binding assay in cells exogenously expressing the human H<sub>3</sub> receptor.

  • Interaction Score: 0.49

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.47

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA