• POZANICLINE chembl:CHEMBL127071

    Alternate Names:

    A-87089.0
    A-870890
    ABT-089
    POZANICLINE

    Drug Info:

    FDA Approval not approved
    Drug Class small molecule
    Drug Indications for treatment of Alzheimer's disease
    (0 More Sources)

    Publications:

  • Interaction Score: 5.32

    Interaction Types & Directionality:
    partial agonist (activating)

    Interaction Info:
    Mechanism of Interaction Neuronal acetylcholine receptor; alpha6/beta2 partial agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 3.99

    Interaction Types & Directionality:
    partial agonist (activating)

    Interaction Info:
    Mechanism of Interaction Nicotinic acetylcholine receptor alpha4/beta2/alpha5 partial agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.99

    Interaction Types & Directionality:
    partial agonist (activating)

    Interaction Info:
    Mechanism of Interaction Nicotinic acetylcholine receptor alpha4/beta2/alpha5 partial agonist
    Direct Interaction yes
    Trial Name pozanicline , ABT-089

    PMIDs:
    None found


  • Interaction Score: 0.78

    Interaction Types & Directionality:
    partial agonist (activating)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Nicotinic acetylcholine receptor alpha4/beta2/alpha5 partial agonist
    Trial Name pozanicline , ABT-089

    PMIDs:
    None found