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PRIMAQUINE Drug Record

  • Summary
  • Interactions
  • Claims
  • PRIMAQUINE chembl:CHEMBL506 Approved

    Alternate Names:

    SN-13272
    PRIMAQUINE
    WR-2975
    NSC-27296

    Drug Info:

    (1 More Sources)

    Publications:

    Kedar P et al., 2014, Primaquine-induced severe methemoglobinemia developed during treatment of Plasmodium vivax malarial infection in an Indian family associated with a novel mutation (p.Agr57Trp) in the CYB5R3 gene., Clin Chim Acta
    Yoshinari K et al., 2008, Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements., Biochem Pharmacol
    Constantino et al., 1999, Metabolism of primaquine by liver homogenate fractions. Evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to carboxyprimaquine., Exp. Toxicol. Pathol.
    Martirosyan et al., 2004, Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model., Biochem. Pharmacol.
  • PRIMAQUINE   CYB5R4

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • PRIMAQUINE   CYB5R1

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • PRIMAQUINE   CYB5R2

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • PRIMAQUINE   IKBKG

    Interaction Score: 1.93

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • PRIMAQUINE   CYB5R3

    Interaction Score: 1.93

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25058800


    Sources:
    PharmGKB

  • PRIMAQUINE   E2F1

    Interaction Score: 0.97

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15450938


    Sources:
    NCI

  • PRIMAQUINE   G6PD

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    FDA

  • PRIMAQUINE   CYP1A2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18502397 10445386


    Sources:
    NCI PharmGKB

  • NCI: PRIMAQUINE

    • Version: 14-September-2017

    Alternate Names:
    C771 NCI drug code

    Drug Info:

    Publications:
    Constantino et al., 1999, Metabolism of primaquine by liver homogenate fractions. Evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to carboxyprimaquine., Exp. Toxicol. Pathol.
    Martirosyan et al., 2004, Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model., Biochem. Pharmacol.

  • PharmGKB: primaquine

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Kedar P et al., 2014, Primaquine-induced severe methemoglobinemia developed during treatment of Plasmodium vivax malarial infection in an Indian family associated with a novel mutation (p.Agr57Trp) in the CYB5R3 gene., Clin Chim Acta
    Yoshinari K et al., 2008, Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements., Biochem Pharmacol

  • TTD: Primaquine

    • Version: 2020.06.01

    Alternate Names:
    D0T1LK TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL506

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • FDA: Primaquine

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21