PRIMIDONE |
LISKANTIN |
NEUROSYN |
MYSOLINE |
NSC-41701 |
LEPSIRAL |
5-PHENYL-5-ETHYL-HEXAHYDROPYRIMIDINE-4,6-DIONE |
MYSOLINE® |
PRIMIDONUM |
PRIMIDON |
PRIMACLONE |
2-DEOXYPHENOBARBITAL |
DESOXYPHENOBARBITAL |
PRIMIDONA |
chembl:CHEMBL856 |
chemidplus:125-33-7 |
rxcui:8691 |
pubchem.compound:4909 |
drugbank:00794 |
Drug Class | anticonvulsants |
Year of Approval | 1954 |
Drug Categories | barbiturates |
FDA Approval | 1954 |
Drug Class | small molecule |
Drug Indications | Anticonvulsants |
Drug Categories | anti-epileptic agent |
Drug Categories | anticholinergic agents |
Drug Categories | cytochrome p-450 cyp1a2 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp2c19 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp2c9 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp2c9 substrates |
Drug Categories | cytochrome p-450 cyp2e1 inducers |
Drug Categories | cytochrome p-450 cyp2e1 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp2e1 substrates |
Drug Categories | cytochrome p-450 cyp3a inducers (strong) |
Drug Categories | cytochrome p-450 cyp3a4 inducers |
Drug Categories | cytochrome p-450 cyp3a4 inducers (strength unknown) |
Drug Categories | cytochrome p-450 enzyme inducers |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | decreased central nervous system disorganized electrical activity |
Drug Categories | enzyme inducing antiepileptic drugs |
Drug Categories | gaba agents |
Drug Categories | gaba modulators |
Drug Categories | hypnotics and sedatives |
Drug Categories | neurotransmitter agents |
Drug Categories | nicotinic antagonists |
Drug Categories | phenobarbital and similars |
Drug Categories | psycholeptics |
Drug Categories | ugt1a1 inducers |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
positive modulator (activating) |
potentiator |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
Trial Name | - |
blocker (inhibitory) |
Specific Action of the Ligand | None |
Endogenous Drug? | False |
Direct Interaction? | False |
positive modulator (activating) |
potentiator |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
potentiator |
Novel drug target | Established target |
Trial Name | - |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
potentiator |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
Trial Name | - |
positive modulator (activating) |
potentiator |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
potentiator |
Novel drug target | Established target |
Trial Name | - |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
PRIMIDONE | DrugBank Drug Name |
125-33-7 | CAS Number |
Liskantin | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Groups | vet_approved |
PRIMIDONE | Primary Drug Name |
Year of Approval | 1954 |
Drug Class | anticonvulsants |
Drug Indications | Anticonvulsants |
Drug Class | small molecule |
FDA Approval | 1954 |
D0U5RT | TTD Drug ID |
CHEMBL856 | ChEMBL Drug ID |
PRIMIDONE | GuideToPharmacology Ligand Name |