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PROCARBAZINE Drug Record

  • Summary
  • Interactions
  • Claims
  • PROCARBAZINE chembl:CHEMBL1321 ApprovedAntineoplasticImmunotherapy

    Alternate Names:

    RO-4-6467
    MATULANE
    PROCARBAZINE
    RO-4-6467 FREE BASE
    RO-4-6467/1
    N-ISOPROPYL-P-(2-METHYLHYDRAZINOMETHYL)-BENZAMIDE
    MATULANE®
    RO-4646711
    N-ISOPROPYL-Α-(2-METHYLHYDRAZINO)-P-TOLUAMIDE
    2-(P-ISOPROPYLCARBAMOYLBENZYL)-1-METHYLHYDRAZINE
    N-(1-METHYLETHYL)-4-((2-METHYLHYDRAZINO)METHYL)BENZAMIDE
    PROCARBAZIN
    N-ISOPROPYL-4-[(2-METHYLHYDRAZINO)METHYL]BENZAMIDE
    4-((2-METHYLHYDRAZINO)METHYL)-N-ISOPROPYLBENZAMIDE
    PROCARBAZINUM
    PROCARBAZINA
    N-4-ISOPROPYLCARBAMOYLBENZYL-N'-METHYLHYDRAZINE
    N-ISOPROPYL-ALPHA-(2-METHYLHYDRAZINO)-P-TOLUAMIDE
    1-METHYL-2-(P-(ISOPROPYLCARBAMOYL)BENZYL)HYDRAZINE
    P-(2-METHYLHYDRAZINOMETHYL)-N-ISOPROPYLBENZAMIDE
    chemidplus:671-16-9
    pubchem.compound:4915
    rxcui:8702
    drugbank:01168
    chembl:CHEMBL1321

    Drug Info:

    (1 More Sources)

    Publications:

    Rassidakis et al., 2002, BAX expression in Hodgkin and Reed-Sternberg cells of Hodgkin's disease: correlation with clinical outcome., Clin. Cancer Res.
    Wiestler et al., 2013, ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis., Acta Neuropathol.
    Aglietta et al., 2000, Short term treatment with Escherichia coli recombinant human granulocyte-macrophage-colony stimulating factor prior to chemotherapy for Hodgkin disease., Cancer
  • PROCARBAZINE   ATRX

    Interaction Score: 2.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23904111


    Sources:
    CIViC

  • PROCARBAZINE   CSF2

    Interaction Score: 0.6

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10640980


    Sources:
    NCI

  • PROCARBAZINE   BAX

    Interaction Score: 0.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11839668


    Sources:
    NCI

  • PROCARBAZINE   ALOX15

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROCARBAZINE   CYP1A2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NCI: PROCARBAZINE

    • Version: 14-September-2017

    Alternate Names:
    C773 NCI drug code

    Drug Info:

    Publications:
    Aglietta et al., 2000, Short term treatment with Escherichia coli recombinant human granulocyte-macrophage-colony stimulating factor prior to chemotherapy for Hodgkin disease., Cancer
    Rassidakis et al., 2002, BAX expression in Hodgkin and Reed-Sternberg cells of Hodgkin's disease: correlation with clinical outcome., Clin. Cancer Res.

  • CIViC: PROCARBAZINE

    • Version: 14-September-2020

    Alternate Names:

    Drug Info:

    Publications:
    Wiestler et al., 2013, ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis., Acta Neuropathol.

  • DTC: PROCARBAZINE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1321 ChEMBL Drug ID

    Drug Info:

    Publications:

  • TTD: Procarbazine

    • Version: 2020.06.01

    Alternate Names:
    D08GYO TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1321

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21