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QUARFLOXIN Drug Record

  • Summary
  • Interactions
  • Claims
  • QUARFLOXIN chembl:CHEMBL3989407

    Alternate Names:

    QUARFLOXIN
    CX-3543
    ITARNAFLOXIN

    Drug Info:

    (0 More Sources)

    Publications:

    Xu et al., 2017, CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours., Nat Commun
    Balasubramanian S et al., 2011, Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?, Nat Rev Drug Discov
  • QUARFLOXIN   NCL

    Interaction Score: 41.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21455236


    Sources:
    TTD

  • QUARFLOXIN   BRCA2

    Interaction Score: 1.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28211448


    Sources:
    CIViC

  • QUARFLOXIN   BRCA1

    Interaction Score: 0.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28211448


    Sources:
    CIViC

  • TTD: Itarnafloxin

    • Version: 2020.06.01

    Alternate Names:
    D09ENR TTD Drug ID

    Drug Info:

    Publications:
    Balasubramanian S et al., 2011, Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?, Nat Rev Drug Discov

  • CIViC: QUARFLOXIN

    • Version: 14-September-2020

    Alternate Names:

    Drug Info:

    Publications:
    Xu et al., 2017, CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours., Nat Commun

  • ChemblDrugs: chembl:CHEMBL3989407

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21