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RIFAXIMIN Drug Record

  • Summary
  • Interactions
  • Claims
  • RIFAXIMIN chembl:CHEMBL1617 Approved

    Alternate Names:

    NORMIX
    RIFAXIDIN
    XIFAXAN
    RIFACOL
    TARGAXAN
    RIFAXIMIN
    XIFAXANTA
    RIFAXIMINUN
    RIFAXIMINA
    RIFAXIMINE
    RIFAMYCIN L 105
    XIFAXSAN
    RIFAXIMINUM
    RIFAMYCIN L 105SV
    rxcui:35619
    drugbank:01220
    chemidplus:80621-81-4
    pubchem.compound:6436173
    chembl:CHEMBL1617

    Drug Info:

    (0 More Sources)

    Publications:

    Festa C et al., 2011, Solomonsterols A and B from Theonella swinhoei. The first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity., J Med Chem
    Sepe V et al., 2012, Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei., J Med Chem
    Sepe V et al., 2014, Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges., Eur J Med Chem
    Hodnik Ž et al., 2014, Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane X receptor antagonists., J Med Chem
    Ma et al., 2007, Rifaximin is a gut-specific human pregnane X receptor activator., J. Pharmacol. Exp. Ther.
    Cheng et al., 2010, Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation., J. Pharmacol. Exp. Ther.
  • RIFAXIMIN   NR1I2

    Interaction Score: 3.9

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:

    PMIDs:
    21141967 22126372 24388834 24828006 17442842 20627999


    Sources:
    DTC

  • DTC: RIFAXIMIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1617 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sepe V et al., 2014, Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges., Eur J Med Chem
    Hodnik Ž et al., 2014, Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane X receptor antagonists., J Med Chem
    Sepe V et al., 2012, Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei., J Med Chem

  • ChemblDrugs: chembl:CHEMBL1617

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21