• Interaction Score: 0.36

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
    Direct Interaction yes
    Reported Cancer Type Melanoma

    PMIDs:
    None found


  • Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal adenocarcinoma
    Response Type decreased response
    Approval Status Preclinical - Cell culture

    PMIDs:
    26438159


    Sources:
    JAX-CKB

  • Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type bladder transitional cell papilloma
    Response Type no benefit
    Approval Status Preclinical - Cell culture

    PMIDs:
    26438159


    Sources:
    JAX-CKB

  • Interaction Score: 0.22

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Dual specificity mitogen-activated protein kinase kinase 2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type no benefit
    Approval Status Phase I


    Sources:
    JAX-CKB

  • Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type non-small cell lung carcinoma
    Indication/Tumor Type lung small cell carcinoma
    Evidence Type Actionable

    PMIDs:
    26438159


    Sources:
    JAX-CKB

  • Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type melanoma
    Response Type sensitive
    Approval Status Preclinical - Cell culture

    PMIDs:
    26438159


    Sources:
    JAX-CKB