DGIdb - ROLIPRAM Drug Record

ROLIPRAM chembl:CHEMBL63

Alternate Names:

ZK-62711
SB-95952
ROLIPRAM
ZK-62771

Drug Info:

(0 More Sources)

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Skoumbourdis AP et al., 2009, Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors., Bioorg Med Chem Lett

ROLIPRAM PDE4D

Interaction Score: 1.77

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
10592235 17016423 17139284

Sources:
TTD
ROLIPRAM PDE4B

Interaction Score: 1.55

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
10592235 17016423 17139284

Sources:
TTD
ROLIPRAM PDE5A

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
ROLIPRAM PDE4A

Interaction Score: 0.41

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
TTD
ROLIPRAM ADRB2

Interaction Score: 0.19

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19464886

Sources:
DTC

DTC: ROLIPRAM
- Version: 02-September-2020
Alternate Names:

CHEMBL63 ChEMBL Drug ID

Drug Info:

Publications:

Skoumbourdis AP et al., 2009, Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors., Bioorg Med Chem Lett
TTD: ROLIPRAM
- Version: 2020.06.01
Alternate Names:

D0T5PO TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL63
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

ROLIPRAM Drug Record

ROLIPRAM chembl:CHEMBL63

Alternate Names:

Drug Info:

Publications:

ROLIPRAM PDE4D

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 10592235 17016423 17139284

Sources: TTD

ROLIPRAM PDE4B

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 10592235 17016423 17139284

Sources: TTD

ROLIPRAM PDE5A

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

ROLIPRAM PDE4A

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: TTD

ROLIPRAM ADRB2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19464886

Sources: DTC

DTC: ROLIPRAM

Alternate Names: CHEMBL63 ChEMBL Drug ID

Drug Info:

Publications: Skoumbourdis AP et al., 2009, Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors., Bioorg Med Chem Lett

TTD: ROLIPRAM

Alternate Names: D0T5PO TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL63

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
10592235 17016423 17139284

Sources:
TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
10592235 17016423 17139284

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
19464886

Sources:
DTC

Alternate Names:

CHEMBL63 ChEMBL Drug ID

Publications:

Skoumbourdis AP et al., 2009, Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors., Bioorg Med Chem Lett

Alternate Names:

D0T5PO TTD Drug ID