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ROPIVACAINE Drug Record

  • Summary
  • Interactions
  • Claims
  • ROPIVACAINE chembl:CHEMBL1077896 Approved

    Alternate Names:

    ROPIVACAINE
    (-)-1-PROPYL-2',6'-PIPECOLOXYLIDIDE
    LEA-103
    AL-381
    (S)-(-)-1-PROPYL-2',6'-PIPECOLOXYLIDIDE
    ROPIVACAINA
    ROPIVACAINUM
    (S)-(−)-1-PROPYL-2',6'-PIPECOLOXYLIDIDE
    (S)-ROPIVACAINE
    NAROPIN®
    ROPIVACAINE HYDROCHLORIDE
    1-PROPYL-2',6'-PIPECOLOXYLIDIDE
    (-)-1-PROPYL-2',6'-DIMETHYL-2-PIPERIDYLCARBOXYANILIDE
    L-N-N-PROPYLPIPECOLIC ACID-2,6-XYLIDIDE
    drugbank:00296
    chembl:CHEMBL1077896
    rxcui:35780
    pubchem.compound:175805
    chemidplus:84057-95-4

    Drug Info:

    Drug Class anesthetics, local
    Year of Approval 1996
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications anestethic
    (2 More Sources)

    Publications:

    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Liu et al., 2000, The effects of ropivacaine on sodium currents in dorsal horn neurons of neonatal rats., Anesth. Analg.
    Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev
  • ROPIVACAINE   CYB5R3

    Interaction Score: 1.93

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • ROPIVACAINE   SCN10A

    Interaction Score: 1.22

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name ropivacaine HCl,Naropin
    Novel drug target Established target

    PMIDs:
    17016423 17139284 10781449


    Sources:
    TdgClinicalTrial TEND TTD

  • ROPIVACAINE   G6PD

    Interaction Score: 0.44

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • ROPIVACAINE   CYP3A4

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9187528


    Sources:
    PharmGKB

  • TEND: ROPIVACAINE

    • Version: 01-August-2011

    Alternate Names:
    ROPIVACAINE Primary Drug Name

    Drug Info:
    Year of Approval 1996
    Drug Class anesthetics, local

    Publications:

  • TdgClinicalTrial: ROPIVACAINE

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications anestethic
    Drug Class Small Molecule
    FDA Approval approved

    Publications:

  • PharmGKB: ropivacaine

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev

  • TTD: Ropivacaine

    • Version: 2020.06.01

    Alternate Names:
    D09RHQ TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1077896

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • FDA: Ropivacaine

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21