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SAQUINAVIR Drug Record

  • Summary
  • Interactions
  • Claims
  • SAQUINAVIR chembl:CHEMBL114 Approved

    Alternate Names:

    RO-318959000
    SCH-52852
    INVIRASE
    SAQUINAVIR
    FORTOVASE
    RO-31-8959
    FORTOVASE®
    INVIRASE®
    SQV
    SAQUINAVIR MESYLATE
    chembl:CHEMBL114
    chemidplus:127779-20-8
    drugbank:01232
    rxcui:83395
    pubchem.compound:441243

    Drug Info:

    (1 More Sources)

    Publications:

    Equils et al., 2004, Human immunodeficiency virus type 1 protease inhibitors block toll-like receptor 2 (TLR2)- and TLR4-Induced NF-kappaB activation., Antimicrob. Agents Chemother.
    Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev
    Boffito et al., 2002, Pharmacokinetics of saquinavir co-administered with cimetidine., J. Antimicrob. Chemother.
  • SAQUINAVIR   CYP7B1

    Interaction Score: 1.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12461038


    Sources:
    NCI

  • SAQUINAVIR   TLR4

    Interaction Score: 1.41

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15388451


    Sources:
    NCI

  • SAQUINAVIR   IL6

    Interaction Score: 0.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15388451


    Sources:
    NCI

  • SAQUINAVIR   NR1I2

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • SAQUINAVIR   ABCB1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • SAQUINAVIR   ATXN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SAQUINAVIR   IDH1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SAQUINAVIR   CYP3A4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9187528


    Sources:
    PharmGKB

  • NCI: SAQUINAVIR

    • Version: 14-September-2017

    Alternate Names:
    C29444 NCI drug code

    Drug Info:

    Publications:
    Boffito et al., 2002, Pharmacokinetics of saquinavir co-administered with cimetidine., J. Antimicrob. Chemother.
    Equils et al., 2004, Human immunodeficiency virus type 1 protease inhibitors block toll-like receptor 2 (TLR2)- and TLR4-Induced NF-kappaB activation., Antimicrob. Agents Chemother.

  • PharmGKB: saquinavir

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev

  • TTD: Saquinavir

    • Version: 2020.06.01

    Alternate Names:
    D0WI3T TTD Drug ID

    Drug Info:

    Publications:

  • DTC: SAQUINAVIR

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL114 ChEMBL Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL114

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21