NSC-701554 |
SELICICLIB |
AL-39256 |
CYC-202 |
R-ROSCOVITINE |
ROSCOVITINE |
CYC202 |
(2R)-2-((9-(1-METHYLETHYL)-6-((PHENYLMETHYL)AMINO)-9H-PURIN-2-YL)AMINO)-1-BUTANOL |
(2R)-2-{[6-(BENZYLAMINO)-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO}BUTAN-1-OL |
(R)-ROSCOVITINE |
(R)-2-((9-(1-METHYLETHYL)-6-((PHENYLMETHYL)AMINO)-9H-PURIN-2-YL)AMINO)-1-BUTANOL |
2-(R)-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE |
chemidplus:186692-46-6 |
pubchem.compound:160355 |
drugbank:06195 |
chembl:CHEMBL14762 |
Drug Class | Kinase Inhibitors |
FDA Approval | not approved |
Drug Class | small molecule |
Drug Indications | antineoplastic agent |
Drug Type | small molecule |
Drug Groups | investigational |
Drug Categories | anti-infective agents |
Drug Categories | antineoplastic agents |
Drug Categories | enzyme inhibitors |
Drug Categories | heterocyclic compounds, fused-ring |
Drug Categories | protein kinase inhibitors |
Drug Categories | purines |
inhibitor (inhibitory) |
Novel drug target | Novel Target |
Trial Name | seliciclib, R-roscovitine, CYC202 |
Mechanism of Interaction | Cyclin-dependent kinase 7 inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Cyclin-dependent kinase 9 inhibitor |
Direct Interaction | yes |
Direct Interaction? | True |
inhibitor (inhibitory) |
Mechanism of Interaction | Cyclin-dependent kinase 1 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Novel drug target | Novel Target |
Trial Name | seliciclib, R-roscovitine, CYC202 |
Details of the Assay for Interaction | CDK2/cyclin A complex used in assay |
inhibitor (inhibitory) |
Mechanism of Interaction | Cyclin-dependent kinase 5 inhibitor |
Direct Interaction | yes |
SELICICLIB | DrugBank Drug Name |
186692-46-6 | CAS Number |
CHEMBL14762 | ChEMBL ID |
Drug Type | small molecule |
Drug Groups | investigational |
Drug Categories | anti-infective agents |
CYC202 | Development Name |
SELICICLIB | Generic Name |
Drug Class | Kinase Inhibitors |
Drug Indications | antineoplastic agent |
Drug Class | small molecule |
FDA Approval | not approved |
CHEMBL14762 | ChEMBL Drug ID |
D05ADP | TTD Drug ID |
SELICICLIB | GuideToPharmacology Ligand Name |