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SILIBININ Drug Record

  • Summary
  • Interactions
  • Claims
  • SILIBININ chembl:CHEMBL1401508

    Alternate Names:

    SILYBIN
    SILIBININ
    SILYMARIN

    Drug Info:

    (0 More Sources)

    Publications:

    Köck K et al., 2013, Interaction of silymarin flavonolignans with organic anion-transporting polypeptides., Drug Metab Dispos
    Zhao H et al., 2011, Identification and initial SAR of silybin: an Hsp90 inhibitor., Bioorg Med Chem Lett
    Tan ZR et al., 2015, The influence of ABCB1 polymorphism C3435T on the pharmacokinetics of silibinin., J Clin Pharm Ther
  • SILIBININ   SLCO2B1

    Interaction Score: 0.57

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23401473


    Sources:
    DTC

  • SILIBININ   SLCO1B3

    Interaction Score: 0.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23401473


    Sources:
    DTC

  • SILIBININ   HSP90AB1

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21273068


    Sources:
    DTC

  • SILIBININ   SLCO1B1

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23401473


    Sources:
    DTC

  • SILIBININ   F2

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SILIBININ   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21273068


    Sources:
    DTC

  • SILIBININ   ABCB1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26595166


    Sources:
    PharmGKB

  • SILIBININ   ALDH1A1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SILIBININ   HSD17B10

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SILIBININ   GMNN

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SILIBININ   EHMT2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SILIBININ   CYP3A4

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DTC: SILIBININ

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1401508 ChEMBL Drug ID

    Drug Info:

    Publications:
    Zhao H et al., 2011, Identification and initial SAR of silybin: an Hsp90 inhibitor., Bioorg Med Chem Lett
    Köck K et al., 2013, Interaction of silymarin flavonolignans with organic anion-transporting polypeptides., Drug Metab Dispos

  • PharmGKB: silibinin

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Tan ZR et al., 2015, The influence of ABCB1 polymorphism C3435T on the pharmacokinetics of silibinin., J Clin Pharm Ther

  • ChemblDrugs: chembl:CHEMBL1401508

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21