DGIdb - SORBINIL Drug Record

SORBINIL chembl:CHEMBL266497

Alternate Names:

NSC-355082
SORBINIL
CP-45634

Drug Info:

Drug Categories	imidazoles
Drug Categories	aldehyde reductase, antagonists & inhibitors
Drug Groups	investigational

(0 More Sources)

Publications:

Maccari R et al., 2014, Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents., Eur J Med Chem
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

SORBINIL AKR1B1

Interaction Score: 1.96

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
10592235 11752352

Sources:
DrugBank GuideToPharmacology
SORBINIL NFKB2

Interaction Score: 0.58

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24819954

Sources:
DTC
SORBINIL RELA

Interaction Score: 0.56

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24819954

Sources:
DTC
SORBINIL NFKB1

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24819954

Sources:
DTC

DrugBank: DB02712
- Version: 5.1.7
Alternate Names:

SORBINIL DrugBank Drug Name

68367-52-2 CAS Number

CHEMBL266497 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Groups investigational

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

DTC: SORBINIL

Version: 02-September-2020

Alternate Names:

CHEMBL266497 ChEMBL Drug ID

Drug Info:

Publications:

Maccari R et al., 2014, Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents., Eur J Med Chem

GuideToPharmacology: 178103987
- Version: 29-September-2020
Alternate Names:

SORBINIL GuideToPharmacology Ligand Name

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL266497
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Specific Action of the Ligand	Inhibition
Endogenous Drug?	False
Direct Interaction?	False

SORBINIL	DrugBank Drug Name
68367-52-2	CAS Number
CHEMBL266497	ChEMBL ID

Drug Type	small molecule
Drug Groups	experimental
Drug Groups	investigational

SORBINIL Drug Record

SORBINIL chembl:CHEMBL266497

Alternate Names:

Drug Info:

Publications:

SORBINIL AKR1B1

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False

PMIDs: 10592235 11752352

Sources: DrugBank GuideToPharmacology

SORBINIL NFKB2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24819954

Sources: DTC

SORBINIL RELA

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24819954

Sources: DTC

SORBINIL NFKB1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24819954

Sources: DTC

DrugBank: DB02712

Alternate Names: SORBINIL DrugBank Drug Name 68367-52-2 CAS Number CHEMBL266497 ChEMBL ID

Drug Info: Drug Type small molecule Drug Groups experimental Drug Groups investigational

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

DTC: SORBINIL

Alternate Names: CHEMBL266497 ChEMBL Drug ID

Drug Info:

Publications: Maccari R et al., 2014, Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents., Eur J Med Chem

GuideToPharmacology: 178103987

Alternate Names: SORBINIL GuideToPharmacology Ligand Name

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL266497

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
10592235 11752352

Sources:
DrugBank GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
24819954

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
24819954

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
24819954

Sources:
DTC

Alternate Names:

SORBINIL DrugBank Drug Name

68367-52-2 CAS Number

CHEMBL266497 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Groups investigational

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

Alternate Names:

CHEMBL266497 ChEMBL Drug ID

Publications:

Maccari R et al., 2014, Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents., Eur J Med Chem

Alternate Names:

SORBINIL GuideToPharmacology Ligand Name