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SORBINIL Drug Record

  • Summary
  • Interactions
  • Claims
  • SORBINIL chembl:CHEMBL266497

    Alternate Names:

    NSC-355082
    SORBINIL
    CP-45634

    Drug Info:

    Drug Categories imidazoles
    Drug Categories aldehyde reductase, antagonists & inhibitors
    Drug Groups investigational
    (0 More Sources)

    Publications:

    Maccari R et al., 2014, Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents., Eur J Med Chem
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
  • SORBINIL   AKR1B1

    Interaction Score: 1.96

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    10592235 11752352


    Sources:
    DrugBank GuideToPharmacology

  • SORBINIL   NFKB2

    Interaction Score: 0.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24819954


    Sources:
    DTC

  • SORBINIL   RELA

    Interaction Score: 0.56

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24819954


    Sources:
    DTC

  • SORBINIL   NFKB1

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24819954


    Sources:
    DTC

  • DrugBank: DB02712

    • Version: 5.1.7

    Alternate Names:
    SORBINIL DrugBank Drug Name
    68367-52-2 CAS Number
    CHEMBL266497 ChEMBL ID

    Drug Info:
    Drug Type small molecule
    Drug Groups experimental
    Drug Groups investigational

    Publications:
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

  • DTC: SORBINIL

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL266497 ChEMBL Drug ID

    Drug Info:

    Publications:
    Maccari R et al., 2014, Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents., Eur J Med Chem

  • GuideToPharmacology: 178103987

    • Version: 29-September-2020

    Alternate Names:
    SORBINIL GuideToPharmacology Ligand Name

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL266497

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2021-04-13