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SULFAMETHOXAZOLE Drug Record

  • Summary
  • Interactions
  • Claims
  • SULFAMETHOXAZOLE chembl:CHEMBL443 Approved

    Alternate Names:

    SULFAMETHOXAZOLE
    STX-608
    SINOMIN
    GANTANOL-DS
    SULPHAMETHOXAZOLE
    RO-42130
    RO-4-2130
    SUPHAMETHOXAZOLE
    ACETYLSULFAMETHOXAZOLE
    UROBAK
    GANTANOL
    SULFAMETHOXAZOLE SODIUM
    NSC-147832
    3-(P-AMINOPHENYLSULFONAMIDO)-5-METHYLISOXAZOLE
    4-AMINO-N-(5-METHYL-3-ISOXAZOLYL)BENZENESULFONAMIDE
    3-SULFANILAMIDO-5-METHYLISOXAZOLE
    GANTANOL (TN)
    SMX
    SMZ
    chemidplus:723-46-6
    chembl:CHEMBL443
    drugbank:01015
    rxcui:10180
    pubchem.compound:5329

    Drug Info:

    (0 More Sources)

    Publications:

    Wang D et al., 2012, Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients., BMC Med Genomics
    Pirmohamed M et al., 2000, Association analysis of drug metabolizing enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole hypersensitivity., Pharmacogenetics
    Wolkenstein P et al., 2000, Prospective evaluation of detoxification pathways as markers of cutaneous adverse reactions to sulphonamides in AIDS., Pharmacogenetics
    Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev
  • SULFAMETHOXAZOLE   GCLC

    Interaction Score: 6.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22824134


    Sources:
    PharmGKB

  • SULFAMETHOXAZOLE   GSTM1

    Interaction Score: 1.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11191886


    Sources:
    PharmGKB

  • SULFAMETHOXAZOLE   G6PD

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Combination therapy Sulfamethoxazole,Trimethoprim

    PMIDs:
    None found


    Sources:
    FDA

  • SULFAMETHOXAZOLE   CYP2C9

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11186133


    Sources:
    PharmGKB

  • SULFAMETHOXAZOLE   CYP3A4

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9187528


    Sources:
    PharmGKB

  • PharmGKB: sulfamethoxazole

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Pirmohamed M et al., 2000, Association analysis of drug metabolizing enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole hypersensitivity., Pharmacogenetics
    Wolkenstein P et al., 2000, Prospective evaluation of detoxification pathways as markers of cutaneous adverse reactions to sulphonamides in AIDS., Pharmacogenetics
    Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev

  • TTD: Sulfamethoxazole

    • Version: 2020.06.01

    Alternate Names:
    D0R9OH TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL443

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • FDA: Sulfamethoxazole

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21