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TACEDINALINE Drug Record

  • Summary
  • Interactions
  • Claims
  • TACEDINALINE chembl:CHEMBL235191

    Alternate Names:

    CI-994
    PD-123654
    GOE-5549
    TACEDINALINE

    Drug Info:

    (0 More Sources)

    Publications:

    Thomas M et al., 2008, Synthesis and biological evaluation of glucuronide prodrugs of the histone deacetylase inhibitor CI-994 for application in selective cancer chemotherapy., Bioorg Med Chem
  • TACEDINALINE   HDAC11

    Interaction Score: 0.56

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Histone deacetylase inhibitor

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC10

    Interaction Score: 0.51

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Histone deacetylase inhibitor
    Direct Interaction yes

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC5

    Interaction Score: 0.48

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Histone deacetylase inhibitor

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC7

    Interaction Score: 0.48

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Histone deacetylase inhibitor
    Direct Interaction yes

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC8

    Interaction Score: 0.46

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Histone deacetylase inhibitor
    Direct Interaction yes

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC3

    Interaction Score: 0.44

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Histone deacetylase inhibitor
    Direct Interaction yes

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC6

    Interaction Score: 0.43

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Histone deacetylase inhibitor
    Direct Interaction yes

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC4

    Interaction Score: 0.43

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Histone deacetylase inhibitor
    Direct Interaction yes

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC2

    Interaction Score: 0.43

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Histone deacetylase inhibitor
    Direct Interaction yes

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Histone deacetylase inhibitor
    Direct Interaction yes

    PMIDs:
    18692397


    Sources:
    DTC ChemblInteractions

  • TACEDINALINE   HDAC9

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18692397


    Sources:
    DTC

  • DTC: TACEDINALINE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL235191 ChEMBL Drug ID

    Drug Info:

    Publications:
    Thomas M et al., 2008, Synthesis and biological evaluation of glucuronide prodrugs of the histone deacetylase inhibitor CI-994 for application in selective cancer chemotherapy., Bioorg Med Chem

  • ChemblDrugs: chembl:CHEMBL235191

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL235191

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21