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TETRACYCLINE Drug Record

  • Summary
  • Interactions
  • Claims
  • TETRACYCLINE chembl:CHEMBL1440

    Alternate Names:

    ACHROMYCIN V
    E701
    TETRACYCLINE
    ECONOMYCIN
    LIQUAMYCIN
    PANMYCIN
    SUSTAMYCIN
    TETRABID ORGANON
    TETRACYN
    NSC-108579
    ACHROMYCIN
    SUPRAMYCIN
    VETQUAMYCIN
    CYCLOPAR
    (4S,4AS,5AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,6,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NAPHTHACENECARBOXAMIDE
    TETRACYCLINUM
    TETRACYCLIN
    ABRAMYCIN
    DESCHLOROBIOMYCIN
    TÉTRACYCLINE
    PANMYCI DONT CAREIQUAMYCIN
    chemidplus:60-54-8
    drugbank:00759
    pubchem.compound:5353990
    rxcui:10395
    chembl:CHEMBL1440

    Drug Info:

    (1 More Sources)

    Publications:

    Hannah et al., 1975, Stabilization of rat liver tyrosine aminotransferase by tetracycline., Biochem. J.
    Hartupee et al., 2007, IL-17 enhances chemokine gene expression through mRNA stabilization., J. Immunol.
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Miura et al., 1998, Enhancement of low density lipoprotein binding to both low density lipoprotein receptor-positive and -negative cells by tetracycline antibiotics., Lipids
    Ishikawa C et al., 2009, Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes., Antimicrob Agents Chemother
  • TETRACYCLINE   SOD1

    Interaction Score: 1.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TETRACYCLINE   F2RL1

    Interaction Score: 1.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19258275


    Sources:
    DTC

  • TETRACYCLINE   TAT

    Interaction Score: 0.92

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2154


    Sources:
    NCI

  • TETRACYCLINE   IL17A

    Interaction Score: 0.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17785852


    Sources:
    NCI

  • TETRACYCLINE   LDLR

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9470171


    Sources:
    NCI

  • TETRACYCLINE   PTPN7

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TETRACYCLINE   HSP90AB1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TETRACYCLINE   NR1I2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • TETRACYCLINE   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TETRACYCLINE   CYP2C9

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • TETRACYCLINE   CYP2C19

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • TETRACYCLINE   ABCB1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • TETRACYCLINE   CYP1A2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • TETRACYCLINE   CYP2D6

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • TETRACYCLINE   CYP3A4

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • NCI: TETRACYCLINE

    • Version: 14-September-2017

    Alternate Names:
    C865 NCI drug code

    Drug Info:

    Publications:
    Miura et al., 1998, Enhancement of low density lipoprotein binding to both low density lipoprotein receptor-positive and -negative cells by tetracycline antibiotics., Lipids
    Keilhack et al., 2000, The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin., J. Biol. Chem.
    Hartupee et al., 2007, IL-17 enhances chemokine gene expression through mRNA stabilization., J. Immunol.

  • DTC: TETRACYCLINE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1440 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Ishikawa C et al., 2009, Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes., Antimicrob Agents Chemother

  • TTD: Tetracycline

    • Version: 2020.06.01

    Alternate Names:
    D08NQZ TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1440

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • PharmGKB: tetracycline

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21