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TIOTROPIUM Drug Record

  • Summary
  • Interactions
  • Claims
  • TIOTROPIUM chembl:CHEMBL1900528 Approved

    Alternate Names:

    TIOTROPIUM
    SPIRIVA
    SPIRIVA RESPIMAT
    BRALTUS
    pubchem.compound:3086655
    chembl:CHEMBL1900528
    chemidplus:186691-13-4
    rxcui:69120
    drugbank:01409

    Drug Info:

    Drug Class bronchodilator agents
    Year of Approval 2004
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications for treatment of cystic fibrosis,for treatment of chronic obstructive pulmonary disorder (COPD)
    (1 More Sources)

    Publications:

    Barnes, 2001, Tiotropium bromide., Expert Opin Investig Drugs
    Barnes et al., 1995, Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease., Life Sci.
    Hansel et al., 2002, Tiotropium bromide: a novel once-daily anticholinergic bronchodilator for the treatment of COPD., Drugs Today
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Park HW et al., 2009, Additive role of tiotropium in severe asthmatics and Arg16Gly in ADRB2 as a potential marker to predict response., Allergy
  • TIOTROPIUM   CHRM3

    Interaction Score: 1.24

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name tiotropium bromide,Spiriva

    PMIDs:
    11281822 10188785 12582447 11752352


    Sources:
    TdgClinicalTrial TEND TTD

  • TIOTROPIUM   CHRM2

    Interaction Score: 0.73

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name tiotropium bromide,Spiriva
    Novel drug target Established target

    PMIDs:
    10188785 12582447


    Sources:
    TdgClinicalTrial

  • TIOTROPIUM   CHRM1

    Interaction Score: 0.59

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name tiotropium bromide,Spiriva
    Novel drug target Established target

    PMIDs:
    10188785 11281822 12582447


    Sources:
    TdgClinicalTrial

  • TIOTROPIUM   ADRB2

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19183167


    Sources:
    PharmGKB

  • TIOTROPIUM   CYP2D6

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • TEND: TIOTROPIUM

    • Version: 01-August-2011

    Alternate Names:
    TIOTROPIUM Primary Drug Name

    Drug Info:
    Year of Approval 2004
    Drug Class bronchodilator agents

    Publications:

  • TdgClinicalTrial: TIOTROPIUM

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications for treatment of cystic fibrosis,for treatment of chronic obstructive pulmonary disorder (COPD)
    Drug Class Small Molecule
    FDA Approval approved

    Publications:

  • PharmGKB: tiotropium

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Park HW et al., 2009, Additive role of tiotropium in severe asthmatics and Arg16Gly in ADRB2 as a potential marker to predict response., Allergy

  • TTD: Tiotropium

    • Version: 2020.06.01

    Alternate Names:
    D0P1WA TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1900528

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21